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• W2743342606 abstract "ABSTRACT There are limited therapeutic options to treat infections caused by vancomycin-resistant Enterococcus faecium (VREfm). The lipoglycopeptide oritavancin exhibits in vitro activity against this pathogen, although its utility against infections caused by VREfm has not been clinically established. In this study, the pharmacodynamic activity of free-drug levels associated with 12 mg/kg/day of daptomycin and a single 1,200-mg dose of oritavancin were determined against three VanA VREfm isolates in an in vitro pharmacokinetic/pharmacodynamic model." @default.
• W2743342606 created "2017-08-17" @default.
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• W2743342606 date "2017-10-01" @default.
• W2743342606 modified "2023-09-27" @default.
• W2743342606 title "Comparative Pharmacodynamics of Single-Dose Oritavancin and Daily High-Dose Daptomycin Regimens against Vancomycin-Resistant Enterococcus faecium Isolates in an <i>In Vitro</i> Pharmacokinetic/Pharmacodynamic Model of Infection" @default.
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• W2743342606 doi "https://doi.org/10.1128/aac.01265-17" @default.
• W2743342606 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5610485" @default.
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