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• W2743359501 abstract "Significance Long-range alignment patterns of fibroblasts have been observed both in vivo and in vitro. However, there has not been much understanding of the underlying mechanism. In this work, we show that these patterns cannot be simply explained by their steric interactions with one another during collisions. Instead, we propose that fibroblasts may collectively align through nonlocal interactions arising from their modification of an underlying ECM. The proposed mechanism explains the observed coalignment between fibroblasts and collagen fibers around tumors and can be tested in future experiments that can image the dynamics of this pattern formation in vivo or in vitro." @default.
• W2743359501 created "2017-08-17" @default.
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• W2743359501 date "2017-08-07" @default.
• W2743359501 modified "2023-10-12" @default.
• W2743359501 title "On the mechanism of long-range orientational order of fibroblasts" @default.
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• W2743359501 doi "https://doi.org/10.1073/pnas.1707210114" @default.
• W2743359501 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5576822" @default.
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