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• W2743398919 abstract "The study evaluated the addition of surgery (S) to radiation (RT) on survival of squamous cell carcinomas (SCC) of tonsillar-fossa (TF) in a modern cohort with similar epidemiology and treatment as current patients.Retrospective analysis utilizing Surveillance, Epidemiology, and End Results (SEER) Program data.For all stages combined TF patients who received S+RT had superior OS (p < 0.01) and DSS (p < 0.01). For each stage OS and DSS was superior for S+RT (p < 0.05). In multivariate analysis, HRs for OS were statistically significantly higher for TF patients (stage 2, 3, and 4) receiving RT alone (p < 0.001).TF SCC patients treated with either S+RT or RT alone between 2004 and 2011 were examined (n = 6,476). Primary outcome measures included overall survival (OS) and disease specific survival (DSS). Cox proportional hazard ratios (HR) were estimated for patients treated with S+RT compared to RT alone.OS and DSS were superior for all stages combined and for stages 2, 3, and 4 in TF patients who received S+RT compared to RT alone." @default.
• W2743398919 created "2017-08-17" @default.
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• W2743398919 date "2017-08-10" @default.
• W2743398919 modified "2023-10-02" @default.
• W2743398919 title "Combined surgery and radiation improves survival of tonsil squamous cell cancers" @default.
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• W2743398919 doi "https://doi.org/10.18632/oncotarget.20122" @default.
• W2743398919 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5762522" @default.
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