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- W2743443266 abstract "Significance Janus particles (JPs) are structures with two distinct faces. This study reports the discovery of an unprecedented class of JPs denoted Janus dendrimersomes (JDSs) coassembled from amphiphilic Janus dendrimers (JDs) with fluorinated, hydrogenated, and hybrid fluorinated–hydrogenated hydrophobic chains. JDSs consist of fluorinated and hydrogenated vesicles connected in a dumbbell-like shape. They appear as one structure in a broader fission-like pathway, which is revealed by varying the ratios of the three JD components. This pathway implies that non–protein-mediated fission and fusion is a likely mechanism by which similar structures form in synthetic and biological systems. These results highlight the potential importance of non–protein-mediated fusion and fission for biology and medicine." @default.
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- W2743443266 date "2017-08-07" @default.
- W2743443266 modified "2023-10-17" @default.
- W2743443266 title "Janus dendrimersomes coassembled from fluorinated, hydrogenated, and hybrid Janus dendrimers as models for cell fusion and fission" @default.
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- W2743443266 doi "https://doi.org/10.1073/pnas.1708380114" @default.
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