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- W2743448986 abstract "Prediction of intrauterine growth disorders represents a compelling challenge for the modern obstetrics because of their linkage with both adverse perinatal outcomes and long-terms effects on good health. According to the timing onset (early versus late in pregnancy, using as traditional cut-off 34 gestational weeks), fetal growth restriction (FGR) shows peculiar predictive, diagnostic and clinical features, forcing to consider both forms as different. In contrast to ealy-onset, antenatal identification of late FGR complication is missed in more than half of all cases, requiring not only improvements in diagnosis using additional parameters to the standard fetal biometry for estimated fetal weight (EFW), but also in the prediction. Promising seem to be some predictive models including maternal characteristics, biophysical and biochemical markers, able to achieve detection rates around 70% at 10% false-positive rate. An excursus on current evidence from well-designed studies about predictive strategies for late FGR will be presented for each of three trimester of pregnancy, clarifying lights and shadows. Combined models and contingent strategy between first and second trimester and early and late third trimester of pregnancy will discussed as potential tools in the management of unselected obstetric population. Optimal timing to perfom the screening for late FGR will be argued using best predictive values achieved and balacing risks and benefits in consideration of severe adverse perinatal and infant outcomes (SAPIO)." @default.
- W2743448986 created "2017-08-17" @default.
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- W2743448986 date "2017-07-01" @default.
- W2743448986 modified "2023-09-22" @default.
- W2743448986 title "IA 9 Prediction of late onset IUGR" @default.
- W2743448986 doi "https://doi.org/10.1016/j.preghy.2017.07.022" @default.
- W2743448986 hasPublicationYear "2017" @default.
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