FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2743689832> ?p ?o ?g. }

• W2743689832 endingPage "296" @default.
• W2743689832 startingPage "282" @default.
• W2743689832 abstract "Effects of ribavirin on the structure of peritubular sheath (PS) of seminiferous tubules and on testicular functions were studied. We found that ribavirin at a dose of 4 mg/kg/day for 4 weeks produced a significant reduction in testosterone level (6.3 ± 0.2; P < 0.001) and in spermatogenic score count (3.8 ± 0.2; P < 0.001) compared to control values. The thickness of PS (17.8 ± 1.13) and tubular lumen perimeter (1024.7 ± 67) was significantly increased compared to controls (10.7 ± 0.70; P < 0.001 and 808 ± 25; P = 0.004, respectively). The length of germinal epithelium (411.8 ± 39) and tubular external diameters (1661.8 ± 115) was significantly reduced compared to control values (708.4 ± 40; P < 0.001 and 2358.8 ± 169; P < 0.001, respectively). The basement membranes (BMs) were thickened with great deposition of collagen. Myoid cells showed altered structure and extracellular matrix revealed disorganization by excessive collagen I and IV accumulation. Testicular damage was established histologically. Evidence of apoptosis was detected in germ cells. There was a significant increase in integrated density of Casp-3 expression (38,121,743 ± 1,763,420; P < 0.001) in seminiferous tubules compared to control (24,788,409 ± 1,900,140). It is concluded that ribavirin can cause alterations of the testicular function and structure with increased apoptosis in the tissues after 4 weeks of administration. The damaging effect could be persuaded by destruction of the peritubular sheath." @default.
• W2743689832 created "2017-08-17" @default.
• W2743689832 creator A5008212440 @default.
• W2743689832 creator A5050544901 @default.
• W2743689832 creator A5066232287 @default.
• W2743689832 creator A5072752068 @default.
• W2743689832 date "2017-08-11" @default.
• W2743689832 modified "2023-09-26" @default.
• W2743689832 title "Structural evaluation of the peritubular sheath of rat’s testes after administration of ribavirin: A possible impact on the testicular function" @default.
• W2743689832 cites W104024384 @default.
• W2743689832 cites W1495477166 @default.
• W2743689832 cites W1597853314 @default.
• W2743689832 cites W196443461 @default.
• W2743689832 cites W1967042123 @default.
• W2743689832 cites W1974655579 @default.
• W2743689832 cites W1986913080 @default.
• W2743689832 cites W1988668403 @default.
• W2743689832 cites W1994317187 @default.
• W2743689832 cites W2001093537 @default.
• W2743689832 cites W2016631424 @default.
• W2743689832 cites W2024318469 @default.
• W2743689832 cites W2029555059 @default.
• W2743689832 cites W2030335230 @default.
• W2743689832 cites W2040678102 @default.
• W2743689832 cites W2052279782 @default.
• W2743689832 cites W2055006115 @default.
• W2743689832 cites W2063340850 @default.
• W2743689832 cites W2069955375 @default.
• W2743689832 cites W2086527238 @default.
• W2743689832 cites W2087964561 @default.
• W2743689832 cites W2094051883 @default.
• W2743689832 cites W2098207172 @default.
• W2743689832 cites W2107836895 @default.
• W2743689832 cites W2114097670 @default.
• W2743689832 cites W2116921558 @default.
• W2743689832 cites W2125622131 @default.
• W2743689832 cites W2130119155 @default.
• W2743689832 cites W2132035145 @default.
• W2743689832 cites W2138008950 @default.
• W2743689832 cites W2140898815 @default.
• W2743689832 cites W2142408145 @default.
• W2743689832 cites W2144088824 @default.
• W2743689832 cites W2152871237 @default.
• W2743689832 cites W2164932855 @default.
• W2743689832 cites W2165122639 @default.
• W2743689832 cites W2169117565 @default.
• W2743689832 cites W2184044670 @default.
• W2743689832 cites W2399648453 @default.
• W2743689832 cites W2401775943 @default.
• W2743689832 cites W2404477686 @default.
• W2743689832 cites W2416574111 @default.
• W2743689832 cites W2460777311 @default.
• W2743689832 cites W2495658451 @default.
• W2743689832 cites W57868476 @default.
• W2743689832 cites W580177226 @default.
• W2743689832 doi "https://doi.org/10.1177/0394632017726261" @default.
• W2743689832 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5815259" @default.
• W2743689832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28799438" @default.
• W2743689832 hasPublicationYear "2017" @default.
• W2743689832 type Work @default.
• W2743689832 sameAs 2743689832 @default.
• W2743689832 citedByCount "18" @default.
• W2743689832 countsByYear W27436898322018 @default.
• W2743689832 countsByYear W27436898322020 @default.
• W2743689832 countsByYear W27436898322021 @default.
• W2743689832 countsByYear W27436898322022 @default.
• W2743689832 countsByYear W27436898322023 @default.
• W2743689832 crossrefType "journal-article" @default.
• W2743689832 hasAuthorship W2743689832A5008212440 @default.
• W2743689832 hasAuthorship W2743689832A5050544901 @default.
• W2743689832 hasAuthorship W2743689832A5066232287 @default.
• W2743689832 hasAuthorship W2743689832A5072752068 @default.
• W2743689832 hasBestOaLocation W27436898321 @default.
• W2743689832 hasConcept C123765429 @default.
• W2743689832 hasConcept C126322002 @default.
• W2743689832 hasConcept C131631996 @default.
• W2743689832 hasConcept C134018914 @default.
• W2743689832 hasConcept C16685009 @default.
• W2743689832 hasConcept C185592680 @default.
• W2743689832 hasConcept C190283241 @default.
• W2743689832 hasConcept C2778466210 @default.
• W2743689832 hasConcept C55493867 @default.
• W2743689832 hasConcept C71924100 @default.
• W2743689832 hasConcept C86803240 @default.
• W2743689832 hasConceptScore W2743689832C123765429 @default.
• W2743689832 hasConceptScore W2743689832C126322002 @default.
• W2743689832 hasConceptScore W2743689832C131631996 @default.
• W2743689832 hasConceptScore W2743689832C134018914 @default.
• W2743689832 hasConceptScore W2743689832C16685009 @default.
• W2743689832 hasConceptScore W2743689832C185592680 @default.
• W2743689832 hasConceptScore W2743689832C190283241 @default.
• W2743689832 hasConceptScore W2743689832C2778466210 @default.
• W2743689832 hasConceptScore W2743689832C55493867 @default.
• W2743689832 hasConceptScore W2743689832C71924100 @default.
• W2743689832 hasConceptScore W2743689832C86803240 @default.
• W2743689832 hasIssue "3" @default.
• W2743689832 hasLocation W27436898321 @default.
• W2743689832 hasLocation W27436898322 @default.

• next