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- W2743704239 abstract "This chapter describes some recent research that was conducted to measure the retention of iodine in persons with underactive (hypo-thyroid), normal (euthyroid), and overactive (hyperthyroid) thyroid glands, and in persons having no thyroid gland (athyreotic). The Human Monitoring Laboratory (HML) has measured the retention of 131I in patients who had received the radioiodine diagnostically. These measurements provided sufficient information so that the biological half-life of iodine could be calculated. The biological half-life of radioiodine in this subset of a North American population is 20% lower than the ICRP recommended 80 days. The whole-body counter is equipped with six sodium iodide doped with thallium (NaI(Tl)) detectors, combined in two triangular arrays. The upper array consists of three detectors that scan above and the lower array of three detectors that scan below the subject. Each detector array is powered by an independent high-voltage supply. The three preamplifiers for the upper array are connected to a dual sum invert amplifier and the three for the lower array to another. A group of athyreotic patients was studied and compared with individuals with intact thyroid glands. The athyreotic subjects had all undergone complete removal of functioning thyroid tissue by a surgical “total thyroidectomy,” followed by administration of the sodium salt of 131I and ablation of any residual thyroid tissue at least 3 months prior to entry into the study." @default.
- W2743704239 created "2017-08-17" @default.
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- W2743704239 date "2009-01-01" @default.
- W2743704239 modified "2023-09-27" @default.
- W2743704239 title "Retention of Iodine in the Body" @default.
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- W2743704239 doi "https://doi.org/10.1016/b978-0-12-374135-6.00018-2" @default.
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