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- W2743707519 abstract "Although fullerenes and fullerenols have been reported to act as strong ant imicrobial agents, recent reports of their effect on single cell eukaryotic microorganisms, such as Saccharomyces cerevisiae, indicate lack of antifungal activity. In order to fill a knowledge gap, we examined antifungal activity of stable aqueous fullerene nC60 nanoparticles and fullerenol C60(OH)24 nanoparticles against Aspergillus flavus, one of the most important food contaminants. Stable aqueous fullerene nC60 and fullerenol C60(OH)24 nanoparticles were prepared according to Markovic et al [1]. A. flavus mycelia have been grown on YES agar during 7 days at 28 °C according to Gandomi et al [2]. Lipid peroxidation products (TBARS) content in A. flavus mycelia was determined according to Luschchak and Gospodaryov [3]. The results revealed no effect of the nanoparticles added to the cultivation media at 10 and 100 ppb, respectively, over a 7-day growth period. Additionally, redox activity of fullerene and fullerenol nanoparticles was investigated by measurement of lipid peroxidation products (TBARS) in A. flavus mycelia. Fullerene and fullerenol nanoparticles had different effects on oxidative stress in the fungus. Whilst nC60 nanoparticles showed slight pro-oxidant activity by increasing TBARS (p<0.05), C60(OH)24 nanoparticles exhibited antioxidant activity and reduced their formation." @default.
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- W2743707519 date "2014-01-01" @default.
- W2743707519 modified "2023-09-27" @default.
- W2743707519 title "Effect of fullerene and fullerenol nanoparticles on Aspergillus flavus growth" @default.
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