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- W2743821253 abstract "A novel lab-on-a-chip (LoC) device based on the combination of an optofluidic component and a polymeric substrate with a smart surface reacting on UV light is presented for the first time. In the dark or under visible light, the surface containing an enzyme fragment is almost inert and visible (VIS) light (i.e. @ 635 nm) propagating through the optofluidic device is mostly unaffected. When the device is exposed to UV light, the smart surface consisting of spiropyran-functionalized polymer brushes reacts with increased hydrophilicity. As a consequence, the polymer brushes are swelling, enhancing the access of reagents to the enclosed enzyme. The enzymatic reaction yields a blue reaction product causing increased absorbance at 635 nm. Here, we demonstrate both the integration of the optofluidic component and the smart surface into a photonic LoC device, its behavior and performance and the reversible nature of the UV activation." @default.
- W2743821253 created "2017-08-17" @default.
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- W2743821253 date "2017-06-01" @default.
- W2743821253 modified "2023-09-25" @default.
- W2743821253 title "Photonic lab-on-a-chip device with UV light responsive smart surfaces" @default.
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- W2743821253 doi "https://doi.org/10.1109/transducers.2017.7994513" @default.
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