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- W2743909547 abstract "Abstract Background: The root bark of Methods: To investigate the anticonvulsant effects and the possible mechanisms of this plant, an aqueous extract of Results: This extract significantly protected mice against bicuculline-induced motor seizures. It provided 80% protection against picrotoxin-induced tonic-clonic seizures, and strongly antagonized convulsions induced by pilocarpine. AEAD also protected 100% of mice against pentylenetetrazole-induced seizures. Flumazenil, a central benzodiazepine receptor antagonist and FG7142, a partial inverse agonist in the benzodiazepine site of the GABA Conclusions: The effects of" @default.
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- W2743909547 date "2017-01-01" @default.
- W2743909547 modified "2023-09-27" @default.
- W2743909547 title "Evidence for the involvement of the GABA-ergic pathway in the anticonvulsant activity of the roots bark aqueous extract of Anthocleista djalonensis A. Chev. (Loganiaceae)" @default.
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- W2743909547 doi "https://doi.org/10.1515/jbcpp-2017-0048" @default.
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