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- W2743993644 abstract "Snake and spider bites, as well as scorpion sting envenoming, are neglected diseases affecting millions of people all over the world. Neurological complications vary according to the offending animal, and are often directly related to toxic effects of the venom, affecting the central nervous system, the neuromuscular transmission, the cardiovascular system, or the coagulation cascade. Snake bite envenoming may result in stroke or muscle paralysis. Metalloproteinases and other substances (common in vipers and colubrids) have anticoagulant or procoagulant activity, and may induce ischemic or hemorrhagic strokes. The venom of elapids is rich in neurotoxins affecting the neuromuscular transmission at either presynaptic or postsynaptic levels. The clinical picture of scorpion sting envenoming is dominated by muscle weakness associated with arterial hypertension, cardiac arrythmias, myocarditis, or pulmonary edema. These manifestations occur as the result of release of catecholamines into the bloodstream or due to direct cardiac toxicity of the venom. Cerebrovascular complications have been reported after the sting of the Indian red scorpion. Intracranial hemorrhages occur in the setting of acute increases in arterial blood pressure related to sympathetic overstimulation, and cerebral infarctions are related to either cerebral hypoperfusion, consumption coagulopathy, vasculitis, or cardiogenic brain embolism. Three main syndromes result from spider bite envenoming: latrodectism, loxoscelism, and funnel-web spider envenoming. Latrodectism is related to neurotoxins present in the venom of widow spiders. Most cases present with headache, lethargy, irritability, myalgia, tremor, fasciculation, or ataxia. Loxoscelism is caused by envenoming by spiders of the family Sicariidae. It may present with a stroke due to a severe coagulopathy. The venom of funnel-web spiders also has neurotoxins that stimulate neurotransmitter release, resulting in sensory disturbances and muscle paralysis. Proper management of the envenomed patient, including prompt transport to the hospital, correction of the hemostatic disorder, ventilatory support, and administration of antivenom, significantly reduce the risk of neurological complications which, in turn, reduce the mortality and improve the functional outcome of survivors." @default.
- W2743993644 created "2017-08-17" @default.
- W2743993644 creator A5070752159 @default.
- W2743993644 date "2013-01-01" @default.
- W2743993644 modified "2023-10-02" @default.
- W2743993644 title "Neurological effects of venomous bites and stings" @default.
- W2743993644 cites W146866709 @default.
- W2743993644 cites W1504830361 @default.
- W2743993644 cites W152230839 @default.
- W2743993644 cites W1527285220 @default.
- W2743993644 cites W1608858185 @default.
- W2743993644 cites W163826404 @default.
- W2743993644 cites W171218443 @default.
- W2743993644 cites W1836508033 @default.
- W2743993644 cites W1909715902 @default.
- W2743993644 cites W1963821573 @default.
- W2743993644 cites W1964774201 @default.
- W2743993644 cites W1966982559 @default.
- W2743993644 cites W1968466247 @default.
- W2743993644 cites W1972900899 @default.
- W2743993644 cites W1973620913 @default.
- W2743993644 cites W1973786851 @default.
- W2743993644 cites W1975182826 @default.
- W2743993644 cites W1977990760 @default.
- W2743993644 cites W1978379245 @default.
- W2743993644 cites W1979872897 @default.
- W2743993644 cites W1981325790 @default.
- W2743993644 cites W1984752406 @default.
- W2743993644 cites W1985085949 @default.
- W2743993644 cites W1985938599 @default.
- W2743993644 cites W1988131472 @default.
- W2743993644 cites W1988202754 @default.
- W2743993644 cites W1989773159 @default.
- W2743993644 cites W1989867208 @default.
- W2743993644 cites W1992143905 @default.
- W2743993644 cites W1992422553 @default.
- W2743993644 cites W1992670328 @default.
- W2743993644 cites W1994268072 @default.
- W2743993644 cites W1994668283 @default.
- W2743993644 cites W1995014586 @default.
- W2743993644 cites W1996322524 @default.
- W2743993644 cites W1998573624 @default.
- W2743993644 cites W2000055314 @default.
- W2743993644 cites W2001021699 @default.
- W2743993644 cites W2001518436 @default.
- W2743993644 cites W2001739683 @default.
- W2743993644 cites W2003103544 @default.
- W2743993644 cites W2003121925 @default.
- W2743993644 cites W2005193218 @default.
- W2743993644 cites W2005446340 @default.
- W2743993644 cites W2007599976 @default.
- W2743993644 cites W2007940881 @default.
- W2743993644 cites W2012220123 @default.
- W2743993644 cites W2017262399 @default.
- W2743993644 cites W2018008296 @default.
- W2743993644 cites W2019707125 @default.
- W2743993644 cites W2020586594 @default.
- W2743993644 cites W2020921331 @default.
- W2743993644 cites W2020987004 @default.
- W2743993644 cites W2023297862 @default.
- W2743993644 cites W2023439627 @default.
- W2743993644 cites W2025638774 @default.
- W2743993644 cites W2025691326 @default.
- W2743993644 cites W2025781858 @default.
- W2743993644 cites W2029729009 @default.
- W2743993644 cites W2031959898 @default.
- W2743993644 cites W2032015475 @default.
- W2743993644 cites W2032352536 @default.
- W2743993644 cites W2035711195 @default.
- W2743993644 cites W2036623023 @default.
- W2743993644 cites W2037022876 @default.
- W2743993644 cites W2037298345 @default.
- W2743993644 cites W2038154532 @default.
- W2743993644 cites W2038260059 @default.
- W2743993644 cites W2038714461 @default.
- W2743993644 cites W2040569773 @default.
- W2743993644 cites W2042170674 @default.
- W2743993644 cites W2043089030 @default.
- W2743993644 cites W2044173628 @default.
- W2743993644 cites W2045188132 @default.
- W2743993644 cites W2049023683 @default.
- W2743993644 cites W2049442069 @default.
- W2743993644 cites W2049896921 @default.
- W2743993644 cites W2050386754 @default.
- W2743993644 cites W2051583331 @default.
- W2743993644 cites W2051760003 @default.
- W2743993644 cites W2052285187 @default.
- W2743993644 cites W2052503135 @default.
- W2743993644 cites W2052735256 @default.
- W2743993644 cites W2052815851 @default.
- W2743993644 cites W2055648970 @default.
- W2743993644 cites W2057283576 @default.
- W2743993644 cites W2057931098 @default.
- W2743993644 cites W2058043650 @default.
- W2743993644 cites W2058782141 @default.
- W2743993644 cites W2059170680 @default.
- W2743993644 cites W2059258542 @default.
- W2743993644 cites W2059380727 @default.