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• W2744083417 abstract "Pet10p is a yeast lipid droplet protein of unknown function. We show that it binds specifically to and is stabilized by droplets containing triacylglycerol (TG). Droplets isolated from cells with a PET10 deletion strongly aggregate, appear fragile, and fuse in vivo when cells are cultured in oleic acid. Pet10p binds early to nascent droplets, and their rate of appearance is decreased in pet10Δ. Moreover, Pet10p functionally interacts with the endoplasmic reticulum droplet assembly factors seipin and Fit2 to maintain proper droplet morphology. The activity of Dga1p, a diacylglycerol acyltransferase, and TG accumulation were both 30–35% lower in the absence of Pet10p. Pet10p contains a PAT domain, a defining property of perilipins, which was not previously known to exist in yeast. We propose that the core functions of Pet10p and other perilipins extend beyond protection from lipases and include the preservation of droplet integrity as well as collaboration with seipin and Fit2 in droplet assembly and maintenance." @default.
• W2744083417 created "2017-08-17" @default.
• W2744083417 creator A5027876296 @default.
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• W2744083417 date "2017-08-11" @default.
• W2744083417 modified "2023-10-16" @default.
• W2744083417 title "Pet10p is a yeast perilipin that stabilizes lipid droplets and promotes their assembly" @default.
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• W2744083417 cites W1831610401 @default.
• W2744083417 cites W1854421050 @default.
• W2744083417 cites W1914512945 @default.
• W2744083417 cites W1966718167 @default.
• W2744083417 cites W1968917541 @default.
• W2744083417 cites W1976525048 @default.
• W2744083417 cites W1977689678 @default.
• W2744083417 cites W1979313147 @default.
• W2744083417 cites W1980783399 @default.
• W2744083417 cites W1984667462 @default.
• W2744083417 cites W1985156966 @default.
• W2744083417 cites W1986170164 @default.
• W2744083417 cites W2001794379 @default.
• W2744083417 cites W2004341529 @default.
• W2744083417 cites W2004863845 @default.
• W2744083417 cites W2007396399 @default.
• W2744083417 cites W2008540803 @default.
• W2744083417 cites W2014100153 @default.
• W2744083417 cites W2015666741 @default.
• W2744083417 cites W2018289835 @default.
• W2744083417 cites W2029476353 @default.
• W2744083417 cites W2035335697 @default.
• W2744083417 cites W2039380477 @default.
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• W2744083417 cites W2053976280 @default.
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• W2744083417 doi "https://doi.org/10.1083/jcb.201610013" @default.
• W2744083417 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5626530" @default.
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• W2744083417 hasPublicationYear "2017" @default.
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