Matches in SemOpenAlex for { <https://semopenalex.org/work/W2744120533> ?p ?o ?g. }
- W2744120533 endingPage "4277" @default.
- W2744120533 startingPage "4256" @default.
- W2744120533 abstract "Summary Plants generate multitude of aldehydes under abiotic and biotic stress conditions. Ample demonstrations have shown that rice‐derived aldehydes enhance the resistance of rice against the rice‐blast fungus Magnaporthe oryzae . However, how the fungal pathogen nullifies the inhibitory effects of host aldehydes to establish compatible interaction remains unknown. Here we identified and evaluated the in vivo transcriptional activities of M. oryzae aldehyde dehydrogenase (ALDH) genes. Transcriptional analysis of M. oryzae ALDH genes revealed that the acetylating enzyme Methylmalonate‐Semialdehyde Dehydrogenase (MoMsdh/MoMmsdh) elevated activities during host invasion and colonization of the fungus. We further examined the pathophysiological importance of MoMSDH by deploying integrated functional genetics, and biochemical approaches. MoMSDH deletion mutant Δ Momsdh exhibited germination defect, hyper‐branching of germ tube and failed to form appressoria on hydrophobic and hydrophilic surface. The MoMSDH disruption caused accumulation of small branch‐chain amino acids, pyridoxine and AMP/cAMP in the Δ Momsdh mutant and altered Spitzenkörper organization in the conidia. We concluded that MoMSDH contribute significantly to the pathogenesis of M. oryzae by regulating the mobilization of Spitzenkörper during germ tube morphogenesis, appressoria formation by acting as metabolic switch regulating small branch‐chain amino acids, inositol, pyridoxine and AMP/cAMP homeostasis." @default.
- W2744120533 created "2017-08-17" @default.
- W2744120533 creator A5003045904 @default.
- W2744120533 creator A5009912372 @default.
- W2744120533 creator A5017840696 @default.
- W2744120533 creator A5021778891 @default.
- W2744120533 creator A5029262546 @default.
- W2744120533 creator A5045448847 @default.
- W2744120533 creator A5046323806 @default.
- W2744120533 creator A5076037840 @default.
- W2744120533 creator A5076466992 @default.
- W2744120533 creator A5082394078 @default.
- W2744120533 creator A5091833058 @default.
- W2744120533 date "2017-09-21" @default.
- W2744120533 modified "2023-10-18" @default.
- W2744120533 title "Methylmalonate‐semialdehyde dehydrogenase mediated metabolite homeostasis essentially regulate conidiation, polarized germination and pathogenesis in <i>Magnaporthe oryzae</i>" @default.
- W2744120533 cites W1151606741 @default.
- W2744120533 cites W1505743758 @default.
- W2744120533 cites W1520323284 @default.
- W2744120533 cites W1546157935 @default.
- W2744120533 cites W1578660672 @default.
- W2744120533 cites W1588480640 @default.
- W2744120533 cites W1900937478 @default.
- W2744120533 cites W1946377245 @default.
- W2744120533 cites W1955146052 @default.
- W2744120533 cites W1963687334 @default.
- W2744120533 cites W1963945069 @default.
- W2744120533 cites W1986280421 @default.
- W2744120533 cites W1988140312 @default.
- W2744120533 cites W1988887160 @default.
- W2744120533 cites W1996842851 @default.
- W2744120533 cites W200193258 @default.
- W2744120533 cites W2003739526 @default.
- W2744120533 cites W2006568893 @default.
- W2744120533 cites W2014680422 @default.
- W2744120533 cites W2024948763 @default.
- W2744120533 cites W2030712753 @default.
- W2744120533 cites W2032010360 @default.
- W2744120533 cites W2032324478 @default.
- W2744120533 cites W2043748080 @default.
- W2744120533 cites W2044960582 @default.
- W2744120533 cites W2048175162 @default.
- W2744120533 cites W2058712650 @default.
- W2744120533 cites W2061414976 @default.
- W2744120533 cites W2063692510 @default.
- W2744120533 cites W2064237100 @default.
- W2744120533 cites W2066369410 @default.
- W2744120533 cites W2068873971 @default.
- W2744120533 cites W2069722153 @default.
- W2744120533 cites W2069963405 @default.
- W2744120533 cites W2070485229 @default.
- W2744120533 cites W2070916151 @default.
- W2744120533 cites W2077261320 @default.
- W2744120533 cites W2080294870 @default.
- W2744120533 cites W2080574609 @default.
- W2744120533 cites W2085320024 @default.
- W2744120533 cites W2086137541 @default.
- W2744120533 cites W2089334150 @default.
- W2744120533 cites W2092982253 @default.
- W2744120533 cites W2093115396 @default.
- W2744120533 cites W2093702186 @default.
- W2744120533 cites W2107995607 @default.
- W2744120533 cites W2110316063 @default.
- W2744120533 cites W2115476123 @default.
- W2744120533 cites W2115727633 @default.
- W2744120533 cites W2118013428 @default.
- W2744120533 cites W2118751052 @default.
- W2744120533 cites W2123665978 @default.
- W2744120533 cites W2134454646 @default.
- W2744120533 cites W2134672058 @default.
- W2744120533 cites W2135197206 @default.
- W2744120533 cites W2143301135 @default.
- W2744120533 cites W2146032647 @default.
- W2744120533 cites W2147526198 @default.
- W2744120533 cites W2151042764 @default.
- W2744120533 cites W2152207030 @default.
- W2744120533 cites W2157878151 @default.
- W2744120533 cites W2158714788 @default.
- W2744120533 cites W2346558733 @default.
- W2744120533 cites W614043002 @default.
- W2744120533 doi "https://doi.org/10.1111/1462-2920.13888" @default.
- W2744120533 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28799697" @default.
- W2744120533 hasPublicationYear "2017" @default.
- W2744120533 type Work @default.
- W2744120533 sameAs 2744120533 @default.
- W2744120533 citedByCount "17" @default.
- W2744120533 countsByYear W27441205332018 @default.
- W2744120533 countsByYear W27441205332019 @default.
- W2744120533 countsByYear W27441205332020 @default.
- W2744120533 countsByYear W27441205332022 @default.
- W2744120533 countsByYear W27441205332023 @default.
- W2744120533 crossrefType "journal-article" @default.
- W2744120533 hasAuthorship W2744120533A5003045904 @default.
- W2744120533 hasAuthorship W2744120533A5009912372 @default.
- W2744120533 hasAuthorship W2744120533A5017840696 @default.
- W2744120533 hasAuthorship W2744120533A5021778891 @default.
- W2744120533 hasAuthorship W2744120533A5029262546 @default.
- W2744120533 hasAuthorship W2744120533A5045448847 @default.