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- W2744133050 abstract "In present study, two hydrolyzed residue polysaccharides (RPS) of enzymatic-RPS (ERPS) and acidic-RPS (ARPS) were successfully obtained from the residue of Lentinula edodes, and the anti-inflammatory as well as antioxidative effects on lipopolysaccharide-induced (LPS-induced) lung injured mice were investigated. The results demonstrated that ERPS showed superior lung protective effects by ameliorating the lung wet-to-dry weight (W/D) ratio, reducing the TNF-α, IL-6, and IL-1β levels in BALF, lowing the pulmonary MPO activity, decreasing the serum C3 and hs-CPR contents, as well as improving the antioxidant status by enhancing pulmonary enzyme activities (SOD, GSH-Px, CAT, and T-AOC) and eliminating the lipid peroxidation (MDA and LPO), respectively. These conclusions indicated that both RPS and its hydrolysates (ARPS and ERPS) might be suitable for functional foods and a potentially effective candidate medicine for the treatment of lung injury." @default.
- W2744133050 created "2017-08-17" @default.
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- W2744133050 date "2018-01-01" @default.
- W2744133050 modified "2023-09-24" @default.
- W2744133050 title "The regulation of inflammation and oxidative status against lung injury of residue polysaccharides by Lentinula edodes" @default.
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- W2744133050 doi "https://doi.org/10.1016/j.ijbiomac.2017.08.008" @default.
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