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- W2744460510 abstract "Introduction in sub-saharian africa, in clinical practice only patients meeting the WHO criteria to start antiretroviral treatment undergone creatinine testing, by lack of reagents. Some patients with renal dysfunction are not diagnosed. Van Griensven et al. developed a clinical prediction score (CPS), to accurately identify Cambodian patients, with median baseline body weight of 49 kg (IQR: 43–55), who need a creatinine test before initiating antiretroviral therapy, based on the post-test probability of renal dysfunction. We evaluated the performance of this CPS for predicting patients at risk of kidney dysfunction (KD) in Brazzaville, Congo. Methods The CPS includes following predictors: age (score +2 if>40 years), body weight (score +2 if 10 g/dL), the alternative CPS includes: age (score +2 if>40 years), body weight (score +2 if Results Among 545 patients, median values was: body weight 55 kg (IQR 48–63), age 38.87 years (33.18–46.21); 76 (13.95%) and 142 (26.06%) patients, respectively for CG1 and CG2, had KD. AUROC was 0.6183 (CPS) and 0.5815 (alternative CPS) for CG1 (p=0.0541), 0.7140 (CPS) and 0.6691 (alternative CPS) for CG2 (p=0.0016). Conclusion Because the baseline body weight of African is high than in Cambodian patients, the CPS must be designed for African patients, it is a useful supplement to clinical judgment in the era of limited resources." @default.
- W2744460510 created "2017-08-17" @default.
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- W2744460510 date "2017-07-01" @default.
- W2744460510 modified "2023-09-28" @default.
- W2744460510 title "P2.29 Performance of a clinical prediction score for targeted creatinine testing in africa" @default.
- W2744460510 doi "https://doi.org/10.1136/sextrans-2017-053264.205" @default.
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