Matches in SemOpenAlex for { <https://semopenalex.org/work/W2744722724> ?p ?o ?g. }
- W2744722724 abstract "Pancreatic cancer is highly lethal malignant tumor with characterised rapid progression, invasiveness and resistance to radiochemotherapy. Transforming growth factor-β (TGF-β) signaling plays a dual role in both pro-tumorigenic and tumor suppressive of pancreatic cancer, depending on tumor stage and microenvironment. TGF-β signaling components alteration are common in pancreatic cancer, and its leading role in tumor formation and metastases has received increased attention. Many therapies have investigated to target TGF-β signaling in the preclinical and clinical setting. In this review, we highlight the dual roles of TGF-β and touch upon the perspectives on therapeutic target of TGF-β signaling in pancreatic cancer." @default.
- W2744722724 created "2017-08-17" @default.
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- W2744722724 date "2017-08-07" @default.
- W2744722724 modified "2023-10-11" @default.
- W2744722724 title "TGF-β in pancreatic cancer initiation and progression: two sides of the same coin" @default.
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- W2744722724 doi "https://doi.org/10.1186/s13578-017-0168-0" @default.
- W2744722724 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5545849" @default.
- W2744722724 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28794854" @default.
- W2744722724 hasPublicationYear "2017" @default.
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