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• W2744857549 abstract "There are screening programs for future risk of cardiovascular disease (CVD) complications in diabetes, but not in subclinical diabetes. In the current screening programs, a hypothetical apparently non-diabetic and nonsmoking 40-year-old single parent, from a low- to middle-income community, with a problem of access or affordability of lipid profile, who has blood pressure=120/80 mmHg, fasting blood sugar 5.8 mmol/L, and total cholesterol/HDL=6.5, has no risk of future CVD and does not require any intervention. On counting numbers, the person has two risk factors, that is, hyperglycemia and hyperlipidemia. Further, considering single parenting as a stress factor, for which there is the propensity for underlying oxidative stress that would feed forward to oxidative damage, the person actually has three risk factors. Thus the person qualifies for intervention. The issue is that a pre-diabetes sufferer is treated like a healthy person in the current screening programs. This chapter revisits a previously published hypothesis that suggests a combination of blood glucose level and an index of oxidative damage to improve CVD screening in pre-diabetes. Significant improvement has occurred on the Framingham and the New Zealand Guidelines Group models. This update is meant to emphasize the need to develop a separate model chart for the screening of CVD risk in people with pre-diabetes or undiagnosed diabetes." @default.
• W2744857549 created "2017-08-17" @default.
• W2744857549 creator A5022233792 @default.
• W2744857549 date "2015-01-01" @default.
• W2744857549 modified "2023-09-26" @default.
• W2744857549 title "Cardiovascular Risk Assessment in Pre-Diabetes" @default.
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• W2744857549 doi "https://doi.org/10.1016/b978-0-12-800093-9.00009-0" @default.
• W2744857549 hasPublicationYear "2015" @default.
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