Matches in SemOpenAlex for { <https://semopenalex.org/work/W2744996841> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2744996841 endingPage "726" @default.
- W2744996841 startingPage "715" @default.
- W2744996841 abstract "Synthetic approaches towards novel 3-pyrazolidinone derivatives functionalized at positions N(1) and/or C(5) were studied. 5-Aminoalkyl-3-pyrazolidinones were prepared in four steps from N -protected glycines via Masamune-Claisen homologation, reduction, O-mesylation, and cyclisation with a hydrazine derivative. The free amines were prepared by acidolytic deprotection. Title compound was also prepared by 'ring switching' transformation of N -Boc-pyrrolin-2(5 H )-one with hydrazine hydrate. Hydrogenolytic deprotection of 5-( N -alkyl- N -Cbz-aminomethyl)pyrazolidine-3-ones followed by cyclisation with CDI gave two novel representatives of perhydroimidazo[1,5- b ]pyrazole, which is an almost unexplored heterocyclic system. Amidation of 3-oxopyrazolidine-5-carboxylic acid gave the corresponding carboxamides in moderate yields. Diastereomeric non-racemic carboxamides obtained from ( S )-AlaOMe and ( S )-ProOMe were separated by MPLC." @default.
- W2744996841 created "2017-08-17" @default.
- W2744996841 creator A5015656271 @default.
- W2744996841 creator A5024263837 @default.
- W2744996841 creator A5057066609 @default.
- W2744996841 creator A5071231201 @default.
- W2744996841 creator A5078274592 @default.
- W2744996841 creator A5082756924 @default.
- W2744996841 creator A5088741158 @default.
- W2744996841 date "2017-12-15" @default.
- W2744996841 modified "2023-09-24" @default.
- W2744996841 title "Synthesis of Novel 3D-Rich α-Amino Acid-Derived 3-Pyrazolidinones" @default.
- W2744996841 doi "https://doi.org/10.17344/acsi.2017.3438" @default.
- W2744996841 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29318293" @default.
- W2744996841 hasPublicationYear "2017" @default.
- W2744996841 type Work @default.
- W2744996841 sameAs 2744996841 @default.
- W2744996841 citedByCount "1" @default.
- W2744996841 countsByYear W27449968412018 @default.
- W2744996841 crossrefType "journal-article" @default.
- W2744996841 hasAuthorship W2744996841A5015656271 @default.
- W2744996841 hasAuthorship W2744996841A5024263837 @default.
- W2744996841 hasAuthorship W2744996841A5057066609 @default.
- W2744996841 hasAuthorship W2744996841A5071231201 @default.
- W2744996841 hasAuthorship W2744996841A5078274592 @default.
- W2744996841 hasAuthorship W2744996841A5082756924 @default.
- W2744996841 hasAuthorship W2744996841A5088741158 @default.
- W2744996841 hasBestOaLocation W27449968411 @default.
- W2744996841 hasConcept C106159729 @default.
- W2744996841 hasConcept C111771559 @default.
- W2744996841 hasConcept C138716334 @default.
- W2744996841 hasConcept C155647269 @default.
- W2744996841 hasConcept C162324750 @default.
- W2744996841 hasConcept C178790620 @default.
- W2744996841 hasConcept C185592680 @default.
- W2744996841 hasConcept C2776597398 @default.
- W2744996841 hasConcept C2777682936 @default.
- W2744996841 hasConcept C2780263894 @default.
- W2744996841 hasConcept C2780349576 @default.
- W2744996841 hasConcept C2780378348 @default.
- W2744996841 hasConcept C2781060337 @default.
- W2744996841 hasConcept C43617362 @default.
- W2744996841 hasConcept C71240020 @default.
- W2744996841 hasConceptScore W2744996841C106159729 @default.
- W2744996841 hasConceptScore W2744996841C111771559 @default.
- W2744996841 hasConceptScore W2744996841C138716334 @default.
- W2744996841 hasConceptScore W2744996841C155647269 @default.
- W2744996841 hasConceptScore W2744996841C162324750 @default.
- W2744996841 hasConceptScore W2744996841C178790620 @default.
- W2744996841 hasConceptScore W2744996841C185592680 @default.
- W2744996841 hasConceptScore W2744996841C2776597398 @default.
- W2744996841 hasConceptScore W2744996841C2777682936 @default.
- W2744996841 hasConceptScore W2744996841C2780263894 @default.
- W2744996841 hasConceptScore W2744996841C2780349576 @default.
- W2744996841 hasConceptScore W2744996841C2780378348 @default.
- W2744996841 hasConceptScore W2744996841C2781060337 @default.
- W2744996841 hasConceptScore W2744996841C43617362 @default.
- W2744996841 hasConceptScore W2744996841C71240020 @default.
- W2744996841 hasLocation W27449968411 @default.
- W2744996841 hasLocation W27449968412 @default.
- W2744996841 hasOpenAccess W2744996841 @default.
- W2744996841 hasPrimaryLocation W27449968411 @default.
- W2744996841 hasRelatedWork W1184296338 @default.
- W2744996841 hasRelatedWork W1563896706 @default.
- W2744996841 hasRelatedWork W2062794911 @default.
- W2744996841 hasRelatedWork W2074611398 @default.
- W2744996841 hasRelatedWork W2187708397 @default.
- W2744996841 hasRelatedWork W2339182987 @default.
- W2744996841 hasRelatedWork W2352078085 @default.
- W2744996841 hasRelatedWork W2744996841 @default.
- W2744996841 hasRelatedWork W2952790273 @default.
- W2744996841 hasRelatedWork W4255578482 @default.
- W2744996841 isParatext "false" @default.
- W2744996841 isRetracted "false" @default.
- W2744996841 magId "2744996841" @default.
- W2744996841 workType "article" @default.