Matches in SemOpenAlex for { <https://semopenalex.org/work/W2745079426> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2745079426 endingPage "45" @default.
- W2745079426 startingPage "38" @default.
- W2745079426 abstract "Malaria remains the most important parasitic disease in sub-Saharan Africa as a cause of morbidity and mortality. Effective management of malaria relies on prompt and accurate diagnosis to guide treatment. The World Health Organization (WHO) recommends that all suspected malaria cases be tested before initiation of treatment, thus diagnosis of malaria requires parasitological confirmation of malaria parasites in the blood of suspected patients. This cross-sectional study conducted at the Ahero County Hospital, Kisumu, Kenya, evaluated the performance of quantitative buffy coat (QBC) (QBC Fluorescence and Staining Technologies™(QBC F.A.S.T.™)-improved QBC system and SD Bioline™ malaria rapid tests) against 'gold standard' (Giemsa blood stained slides microscopy) for the detection of Plasmodium species in children<five years old (n=385)in a malaria holo-endemic area of western Kenya. Real-time PCR was performed on discrepant samples across the tests and the gold standard (microscopy).Sensitivity of QBC, QBC F.A.S.T.™ and SD Bioline™ malaria rapid tests were 90% (95% CI: 85-94), 77% (95% CI: 71-83) and 91% (95% CI: 86-94), respectively, while specificity was 30% (95% CI: 24-37), 83% (95% CI: 77-88) and 67% (95% CI: 60-73), respectively. The positive predictive values (PPV) were 58% (95% CI: 52-63), 83% (95% CI: 77-88) and 74% (95% CI: 63-80), respectively, while the negative predictive values (NPV) were 74% (95% CI: 63-84), 78% (95% CI: 71-83) and 87% (95% CI: 81-92), respectively.Although the standard QBC malaria test and the SD Bioline™ malaria rapid diagnostic test (RDT) showed better sensitivity relative to the improved QBC F.A.S.T.™ test, the latter had a better specificity. The performance of these tests remains modest against microscopy. Keywords: Malaria, Quantitative buffy coat, QBC F.A.S.T.™, SD Bioline™" @default.
- W2745079426 created "2017-08-17" @default.
- W2745079426 creator A5014825317 @default.
- W2745079426 creator A5025541170 @default.
- W2745079426 creator A5026220786 @default.
- W2745079426 creator A5029276384 @default.
- W2745079426 creator A5040670576 @default.
- W2745079426 creator A5052841161 @default.
- W2745079426 creator A5069843611 @default.
- W2745079426 creator A5077124817 @default.
- W2745079426 date "2017-01-01" @default.
- W2745079426 modified "2023-09-27" @default.
- W2745079426 title "Performance of Quantitative Buffy Coat, QBC Fluorescence and Staining Technologies™ Test, and SD Bioline™ Malaria Rapid Test in Malaria Diagnosis in Western Kenya" @default.
- W2745079426 hasPublicationYear "2017" @default.
- W2745079426 type Work @default.
- W2745079426 sameAs 2745079426 @default.
- W2745079426 citedByCount "0" @default.
- W2745079426 crossrefType "journal-article" @default.
- W2745079426 hasAuthorship W2745079426A5014825317 @default.
- W2745079426 hasAuthorship W2745079426A5025541170 @default.
- W2745079426 hasAuthorship W2745079426A5026220786 @default.
- W2745079426 hasAuthorship W2745079426A5029276384 @default.
- W2745079426 hasAuthorship W2745079426A5040670576 @default.
- W2745079426 hasAuthorship W2745079426A5052841161 @default.
- W2745079426 hasAuthorship W2745079426A5069843611 @default.
- W2745079426 hasAuthorship W2745079426A5077124817 @default.
- W2745079426 hasConcept C126322002 @default.
- W2745079426 hasConcept C142724271 @default.
- W2745079426 hasConcept C154488023 @default.
- W2745079426 hasConcept C203014093 @default.
- W2745079426 hasConcept C2778048844 @default.
- W2745079426 hasConcept C2778285947 @default.
- W2745079426 hasConcept C2778371730 @default.
- W2745079426 hasConcept C2779810223 @default.
- W2745079426 hasConcept C40993552 @default.
- W2745079426 hasConcept C71924100 @default.
- W2745079426 hasConceptScore W2745079426C126322002 @default.
- W2745079426 hasConceptScore W2745079426C142724271 @default.
- W2745079426 hasConceptScore W2745079426C154488023 @default.
- W2745079426 hasConceptScore W2745079426C203014093 @default.
- W2745079426 hasConceptScore W2745079426C2778048844 @default.
- W2745079426 hasConceptScore W2745079426C2778285947 @default.
- W2745079426 hasConceptScore W2745079426C2778371730 @default.
- W2745079426 hasConceptScore W2745079426C2779810223 @default.
- W2745079426 hasConceptScore W2745079426C40993552 @default.
- W2745079426 hasConceptScore W2745079426C71924100 @default.
- W2745079426 hasLocation W27450794261 @default.
- W2745079426 hasOpenAccess W2745079426 @default.
- W2745079426 hasPrimaryLocation W27450794261 @default.
- W2745079426 hasRelatedWork W177079299 @default.
- W2745079426 hasRelatedWork W2025044302 @default.
- W2745079426 hasRelatedWork W2075212387 @default.
- W2745079426 hasRelatedWork W2123207855 @default.
- W2745079426 hasRelatedWork W2148504980 @default.
- W2745079426 hasRelatedWork W2154796535 @default.
- W2745079426 hasRelatedWork W2464642955 @default.
- W2745079426 hasRelatedWork W2581264398 @default.
- W2745079426 hasRelatedWork W2610217793 @default.
- W2745079426 hasRelatedWork W2611216251 @default.
- W2745079426 hasRelatedWork W2623967825 @default.
- W2745079426 hasRelatedWork W2902520845 @default.
- W2745079426 hasRelatedWork W2905383136 @default.
- W2745079426 hasRelatedWork W2922420019 @default.
- W2745079426 hasRelatedWork W3087727489 @default.
- W2745079426 hasRelatedWork W3096821705 @default.
- W2745079426 hasRelatedWork W3121809224 @default.
- W2745079426 hasRelatedWork W3182446922 @default.
- W2745079426 hasRelatedWork W3199823436 @default.
- W2745079426 hasRelatedWork W2187744073 @default.
- W2745079426 hasVolume "40" @default.
- W2745079426 isParatext "false" @default.
- W2745079426 isRetracted "false" @default.
- W2745079426 magId "2745079426" @default.
- W2745079426 workType "article" @default.