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• W2745117456 abstract "Viral load (VL) monitoring for people on antiretroviral therapy (ART) is extremely challenging in resource-limited settings. We assessed the VL testing scale-up in six Médecins Sans Frontières supported health centres in Maputo, Mozambique, during 2014-15.In a retrospective cohort study, routine programme data were used to describe VL testing uptake and results, and multi-variate logistical regression to estimate predictors of VL testing uptake and suppression.Uptake of a first VL test was 40% (17 236/43 579). Uptake of a follow-up VL test for patients with a high first VL result was 35% (1095/3100). Factors associated with a higher uptake included: age below 15 years, longer time on ART and attending tailored service delivery platforms. Virological suppression was higher in pregnant/breastfeeding women and in community ART Group members. Patients with a high first VL result (18%; 3100/17 236) were mostly younger, had been on ART longer or had tuberculosis. Out of 1095 attending for a follow-up VL test, 678 (62%) had virological failure. Of those, less than one-third had started second line ART.This was the first study describing the uptake and results of VL testing scale-up in Mozambique. Identified gaps show patient and programmatic challenges. Where service delivery was customized to patient needs, VL monitoring was more successful." @default.
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• W2745117456 date "2017-07-01" @default.
• W2745117456 modified "2023-09-27" @default.
• W2745117456 title "Journey towards universal viral load monitoring in Maputo, Mozambique: many gaps, but encouraging signs" @default.
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• W2745117456 doi "https://doi.org/10.1093/inthealth/ihx021" @default.
• W2745117456 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5881256" @default.
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