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- W2745621710 abstract "The purpose of this study was to analyze prospectively clinical and economic effects of vaccination of COPD patients using conjugated pneumococcal vaccine P С V13 (Prevenar 13). Methods. The study involved 39 4 male patients treated in the Teaching Hospital No.4 and Chelyabinsk Pulmonary Center in 2012 – 2016. Number of COPD exacerbations, hospitalizations and cases of pneumonia was analyzed; dyspnea and lung function were also measured; BODE, DOSE, and ADO prognostic indices were calculated. The cost-efficacy of vaccination was assessed. Results. Vaccination with P С V13 vaccine allowed stabilization basic respiratory functional parameters. In a year after the vaccination, BODE, DOSE, and ADO indices significantly decreased and this effect maintained during four years. Number of infectious exacerbations and pneumonia cases significantly decreased in 4 years after vaccination in non-smoking patients. Conclusion. The prognostic indices are a reliable tool to evaluate efficacy of treatment. Vaccination allowed saving up to RUR 394.3 million (78.5 % ) per a year due to reduction in number of COPD exacerbations and rate of pneumonia." @default.
- W2745621710 created "2017-08-31" @default.
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- W2745621710 date "2017-01-01" @default.
- W2745621710 modified "2023-09-30" @default.
- W2745621710 title "Epidemiological characteristics of chronic respiratory diseases in patients vaccinated against pneumococcal infection" @default.
- W2745621710 doi "https://doi.org/10.18093/0869-0189-2017-27-3-376-383" @default.
- W2745621710 hasPublicationYear "2017" @default.
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