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• W2745994324 abstract "Cleft lip and palate is the genetic malformation with the highest incidence of 1:700 of the face. It is the non-fusion of the body’s natural structures that form before birth and affects either the lip, the alveolus, or the palate. Periodontitis is the disease of the supporting tissues of the teeth leading to destruction of the alveolus and secondary edentulism. Osteonecrosis of the jaws related to medication like bisphosphonates (BP) and the RANKL-RANK antagonist denosumab influences bone metabolism and may lead to jaw necrosis, infection, and fracture. Since bone morphogenetic proteins (BMPs) increase the differentiation and proliferation of the mesenchymal stem cell line of osteoblasts, recently they became therapeutic targets to promote bone regeneration. BMPs are already applied for elective surgery in bone regenerative surgical procedures. The efficacy of these surgical procedures is of great scientific concern." @default.
• W2745994324 created "2017-08-31" @default.
• W2745994324 creator A5028716261 @default.
• W2745994324 date "2017-01-01" @default.
• W2745994324 modified "2023-09-25" @default.
• W2745994324 title "Oral and Maxillofacial Aspects of Bone Research" @default.
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• W2745994324 doi "https://doi.org/10.1007/978-3-319-58955-8_8" @default.
• W2745994324 hasPublicationYear "2017" @default.
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