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- W2746091489 abstract "Symbiotic bacteria may dampen the impacts of infectious diseases on hosts by inhibiting pathogen growth. However, our understanding of the generality of pathogen inhibition by different bacterial taxa across pathogen genotypes and environmental conditions is limited. Bacterial inhibitory properties are of particular interest for the amphibian-killing fungal pathogens (Batrachochytrium dendrobatidis and Batrachochytrium salamandrivorans), for which probiotic applications as conservation strategies have been proposed. We quantified the inhibition strength of five putatively B. dendrobatidis-inhibitory bacteria isolated from woodland salamander skin against six Batrachochytrium genotypes at two temperatures (12 and 18°C). We selected six genotypes from across the Batrachochytrium phylogeny: B. salamandrivorans, B. dendrobatidis-Brazil and four genotypes of the B. dendrobatidis Global Panzootic Lineage (GPL1: JEL647, JEL404; GPL2: SRS810, JEL423). We performed 96-well plate challenge assays in a full factorial design. We detected a Batrachochytrium genotype by temperature interaction on bacterial inhibition score for all bacteria, indicating that bacteria vary in ability to inhibit Batrachochytrium depending on pathogen genotype and temperature. Acinetobacter rhizosphaerae moderately inhibited B. salamandrivorans at both temperatures (μ = 46-53%), but not any B. dendrobatidis genotypes. Chryseobacterium sp. inhibited three Batrachochytrium genotypes at both temperatures (μ = 5-71%). Pseudomonas sp. strain 1 inhibited all Batrachochytrium genotypes at 12°C and four Batrachochytrium genotypes at 18°C (μ = 5-100%). Pseudomonas sp. strain 2 and Stenotrophomonas sp. moderately to strongly inhibited all six Batrachochytrium genotypes at both temperatures (μ = 57-100%). All bacteria consistently inhibited B. salamandrivorans. Using cluster analysis of inhibition scores, we found that more closely related Batrachochytrium genotypes grouped together, suggesting that bacterial inhibition strength may be predictable based on Batrachochytrium relatedness. We conclude that bacterial inhibition capabilities change among bacterial strains, Batrachochytrium genotypes and temperatures. A comprehensive understanding of bacterial inhibitory function, across pathogen genotypes and temperatures, is needed to better predict the role of bacterial symbionts in amphibian disease ecology. For targeted conservation applications, we recommend using bacterial strains identified as strongly inhibitory as they are most likely to produce broad-spectrum antimicrobial agents at a range of temperatures." @default.
- W2746091489 created "2017-08-31" @default.
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- W2746091489 date "2017-08-21" @default.
- W2746091489 modified "2023-10-17" @default.
- W2746091489 title "Inhibition of Fungal Pathogens across Genotypes and Temperatures by Amphibian Skin Bacteria" @default.
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- W2746091489 cites W1826308591 @default.
- W2746091489 cites W1951724000 @default.
- W2746091489 cites W1955397794 @default.
- W2746091489 cites W1972395536 @default.
- W2746091489 cites W1974030188 @default.
- W2746091489 cites W1981865703 @default.
- W2746091489 cites W1987424631 @default.
- W2746091489 cites W1987756752 @default.
- W2746091489 cites W1995540767 @default.
- W2746091489 cites W1999959871 @default.
- W2746091489 cites W2009156161 @default.
- W2746091489 cites W2011783070 @default.
- W2746091489 cites W2011920234 @default.
- W2746091489 cites W2017649059 @default.
- W2746091489 cites W2029070593 @default.
- W2746091489 cites W2031308814 @default.
- W2746091489 cites W2036922924 @default.
- W2746091489 cites W2039645459 @default.
- W2746091489 cites W2042562061 @default.
- W2746091489 cites W2043340879 @default.
- W2746091489 cites W2049072621 @default.
- W2746091489 cites W2054444215 @default.
- W2746091489 cites W2054449096 @default.
- W2746091489 cites W2058127090 @default.
- W2746091489 cites W2067026643 @default.
- W2746091489 cites W2068464082 @default.
- W2746091489 cites W2071408913 @default.
- W2746091489 cites W2071513599 @default.
- W2746091489 cites W2071849486 @default.
- W2746091489 cites W2075474494 @default.
- W2746091489 cites W2076433636 @default.
- W2746091489 cites W2078835248 @default.
- W2746091489 cites W2083260831 @default.
- W2746091489 cites W2087553447 @default.
- W2746091489 cites W2105291817 @default.
- W2746091489 cites W2109230082 @default.
- W2746091489 cites W2109538719 @default.
- W2746091489 cites W2111426833 @default.
- W2746091489 cites W2114433329 @default.
- W2746091489 cites W2114835024 @default.
- W2746091489 cites W2116531668 @default.
- W2746091489 cites W2125722060 @default.
- W2746091489 cites W2130378728 @default.
- W2746091489 cites W2133707124 @default.
- W2746091489 cites W2135333204 @default.
- W2746091489 cites W2136506792 @default.
- W2746091489 cites W2139607253 @default.
- W2746091489 cites W2151049058 @default.
- W2746091489 cites W2151617451 @default.
- W2746091489 cites W2154337567 @default.
- W2746091489 cites W2155305301 @default.
- W2746091489 cites W2155735353 @default.
- W2746091489 cites W2162530050 @default.
- W2746091489 cites W2163786118 @default.
- W2746091489 cites W2167232079 @default.
- W2746091489 cites W2172861511 @default.
- W2746091489 cites W2176434024 @default.
- W2746091489 cites W2293498861 @default.
- W2746091489 cites W2312645607 @default.
- W2746091489 cites W2559784664 @default.
- W2746091489 cites W2564041001 @default.
- W2746091489 cites W2586534317 @default.
- W2746091489 cites W2588587638 @default.
- W2746091489 cites W2594079159 @default.
- W2746091489 cites W2601552274 @default.
- W2746091489 cites W2606025176 @default.
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- W2746091489 doi "https://doi.org/10.3389/fmicb.2017.01551" @default.
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