Matches in SemOpenAlex for { <https://semopenalex.org/work/W2746234292> ?p ?o ?g. }
- W2746234292 endingPage "1220" @default.
- W2746234292 startingPage "1210" @default.
- W2746234292 abstract "Secondary palatogenesis occurs when the bilateral palatal shelves (PS), arising from maxillary prominences, fuse at the midline, forming the hard and soft palate. This embryonic phenomenon involves a complex array of morphogenetic events that require coordinated proliferation, apoptosis, migration, and adhesion in the PS epithelia and underlying mesenchyme. When the delicate process of craniofacial morphogenesis is disrupted, the result is orofacial clefting, including cleft lip and cleft palate (CL/P). Through human genetic and animal studies, there are now hundreds of known genetic alternations associated with orofacial clefts; so, it is not surprising that CL/P is among the most common of all birth defects. In recent years, in vitro cell-based assays, ex vivo palate cultures, and genetically engineered animal models have advanced our understanding of the developmental and cell biological pathways that contribute to palate closure. This is particularly true for the areas of PS patterning and growth as well as medial epithelial seam dissolution during palatal fusion. Here, we focus on epithelial cell-cell adhesion, a critical but understudied process in secondary palatogenesis, and provide a review of the available tools and mouse models to better understand this phenomenon." @default.
- W2746234292 created "2017-08-31" @default.
- W2746234292 creator A5017463335 @default.
- W2746234292 creator A5036536036 @default.
- W2746234292 creator A5060898754 @default.
- W2746234292 creator A5066775807 @default.
- W2746234292 date "2017-08-17" @default.
- W2746234292 modified "2023-10-14" @default.
- W2746234292 title "Closing the Gap: Mouse Models to Study Adhesion in Secondary Palatogenesis" @default.
- W2746234292 cites W1185199708 @default.
- W2746234292 cites W118632756 @default.
- W2746234292 cites W1482923899 @default.
- W2746234292 cites W1521875254 @default.
- W2746234292 cites W1603263503 @default.
- W2746234292 cites W1812133033 @default.
- W2746234292 cites W1830098218 @default.
- W2746234292 cites W1830683955 @default.
- W2746234292 cites W1923430647 @default.
- W2746234292 cites W1966896278 @default.
- W2746234292 cites W1969891737 @default.
- W2746234292 cites W1973667655 @default.
- W2746234292 cites W1976923948 @default.
- W2746234292 cites W1985718502 @default.
- W2746234292 cites W1986394650 @default.
- W2746234292 cites W1989699495 @default.
- W2746234292 cites W1994665200 @default.
- W2746234292 cites W2000099020 @default.
- W2746234292 cites W2001593340 @default.
- W2746234292 cites W2004368568 @default.
- W2746234292 cites W2009303644 @default.
- W2746234292 cites W2011842366 @default.
- W2746234292 cites W2012338206 @default.
- W2746234292 cites W2013891209 @default.
- W2746234292 cites W2015411228 @default.
- W2746234292 cites W2018539079 @default.
- W2746234292 cites W2021443187 @default.
- W2746234292 cites W2025530486 @default.
- W2746234292 cites W2032424244 @default.
- W2746234292 cites W2035181275 @default.
- W2746234292 cites W2038970717 @default.
- W2746234292 cites W2038977882 @default.
- W2746234292 cites W2039888453 @default.
- W2746234292 cites W2047725245 @default.
- W2746234292 cites W2047792151 @default.
- W2746234292 cites W2053479367 @default.
- W2746234292 cites W2061423969 @default.
- W2746234292 cites W2063010288 @default.
- W2746234292 cites W2063652013 @default.
- W2746234292 cites W2065321703 @default.
- W2746234292 cites W2069340908 @default.
- W2746234292 cites W2072064870 @default.
- W2746234292 cites W2079834177 @default.
- W2746234292 cites W2084663390 @default.
- W2746234292 cites W2088287802 @default.
- W2746234292 cites W2089212079 @default.
- W2746234292 cites W2093611018 @default.
- W2746234292 cites W2098039703 @default.
- W2746234292 cites W2102298903 @default.
- W2746234292 cites W2102691378 @default.
- W2746234292 cites W2109826010 @default.
- W2746234292 cites W2114712805 @default.
- W2746234292 cites W2124075491 @default.
- W2746234292 cites W2125967439 @default.
- W2746234292 cites W2127711467 @default.
- W2746234292 cites W2128492601 @default.
- W2746234292 cites W2132650229 @default.
- W2746234292 cites W2136790893 @default.
- W2746234292 cites W2137089323 @default.
- W2746234292 cites W2137876744 @default.
- W2746234292 cites W2138338290 @default.
- W2746234292 cites W2141426537 @default.
- W2746234292 cites W2142399350 @default.
- W2746234292 cites W2142960538 @default.
- W2746234292 cites W2145371609 @default.
- W2746234292 cites W2145470537 @default.
- W2746234292 cites W2149879796 @default.
- W2746234292 cites W2155438840 @default.
- W2746234292 cites W2155935761 @default.
- W2746234292 cites W2157640147 @default.
- W2746234292 cites W2161613003 @default.
- W2746234292 cites W2163344736 @default.
- W2746234292 cites W2167298693 @default.
- W2746234292 cites W2171376303 @default.
- W2746234292 cites W2269834552 @default.
- W2746234292 cites W2306395363 @default.
- W2746234292 cites W2335106556 @default.
- W2746234292 cites W2405627334 @default.
- W2746234292 cites W2436099987 @default.
- W2746234292 cites W2464915778 @default.
- W2746234292 cites W2464971150 @default.
- W2746234292 cites W2559805231 @default.
- W2746234292 cites W2560346155 @default.
- W2746234292 cites W2626234955 @default.
- W2746234292 cites W2915391685 @default.
- W2746234292 cites W4212811418 @default.
- W2746234292 doi "https://doi.org/10.1177/0022034517726284" @default.
- W2746234292 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5613886" @default.
- W2746234292 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28817360" @default.