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- W2746460063 abstract "ABSTRACTThe present article compares two treatments, say A and B, in the context of a clinical trial. Let X and Y be, respectively, the responses corresponding to A and B which have some continuous distributions. Here, the comparison is done through the parameter θ=P(X<Y) which is a very common functional in the context of reliability theory and survival analysis. We consider a two-stage data-dependent adaptive allocation design where the observations on X and Y are collected sequentially in two stages. We use the Mann–Whitney–Wilcoxon (MWW) statistic to provide a statistical comparison by a nonparametric approach. Various asymptotic results related to the proposed procedure are studied. The proposed procedure is also compared with the usual single-stage equal allocation design through statistical and clinical performances of the respective allocation procedures." @default.
- W2746460063 created "2017-08-31" @default.
- W2746460063 creator A5038946841 @default.
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- W2746460063 date "2017-08-23" @default.
- W2746460063 modified "2023-09-24" @default.
- W2746460063 title "A comparison between two treatments in a clinical trial with an ethical allocation design" @default.
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- W2746460063 doi "https://doi.org/10.1080/00949655.2017.1367394" @default.
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