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- W2746612228 abstract "Publisher Summary EEG is a measure of a neuronal activity, whereas fMRI reflects hemodynamic changes, in particularthe blood oxygen level–dependent (BOLD) signal, which is the main contrast mechanism exploited by fMRI. This chapter reviews the results of the application of EEG-fMRI in patients with both focal and generalized epilepsy. Central to the technique is the modeling of the BOLD signal based on the observed EEG, which forms a large part of the discussion in the chapter. This has important implications for not only the technique's sensitivity, and therefore its potential clinical usefulness, but also for the understanding of the relationship between EEG activity and brain hemodynamics. The simultaneous recording of EEG and fMRI is a useful noninvasive research method uniquely capable of revealing hemodynamic changes related to epileptic events, often suggestive of a network of pathological activity in both focal and generalized epilepsies. The technique's evaluation as a clinical tool will require further validation studies in patients undergoing presurgical evaluation, and it may also have a key role in furthering the understanding of epileptic networks." @default.
- W2746612228 created "2017-08-31" @default.
- W2746612228 creator A5022017012 @default.
- W2746612228 creator A5084741668 @default.
- W2746612228 date "2009-01-01" @default.
- W2746612228 modified "2023-09-25" @default.
- W2746612228 title "EEG-Correlated fMRI in Epilepsy" @default.
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