Matches in SemOpenAlex for { <https://semopenalex.org/work/W2747492066> ?p ?o ?g. }
- W2747492066 endingPage "11" @default.
- W2747492066 startingPage "1" @default.
- W2747492066 abstract "Stem cell therapy is a promising potential therapeutic strategy to treat cerebral ischemia in preclinical and clinical trials. Currently proposed treatments for stroke employing stem cells include the replacement of lost neurons and integration into the existing host circuitry, the release of growth factors to support and promote endogenous repair processes, and the secretion of extracellular vesicles containing proteins, noncoding RNA, or DNA to regulate gene expression in recipient cells and achieve immunomodulation. Progress has been made to elucidate the precise mechanisms underlying stem cell therapy and the homing, migration, distribution, and differentiation of transplanted stem cells in vivo using various imaging modalities. Noninvasive and safe tracer agents with high sensitivity and image resolution must be combined with long-term monitoring using imaging technology to determine the optimal therapy for stroke in terms of administration route, dosage, and timing. This review discusses potential therapeutic mechanisms of stem cell transplantation for the treatment of stroke and the limitations of current therapies. Methods to label transplanted cells and existing imaging systems for stem cell labeling and in vivo tracking will also be discussed." @default.
- W2747492066 created "2017-08-31" @default.
- W2747492066 creator A5011257788 @default.
- W2747492066 creator A5053046982 @default.
- W2747492066 date "2017-01-01" @default.
- W2747492066 modified "2023-10-18" @default.
- W2747492066 title "Potential Therapeutic Mechanisms and Tracking of Transplanted Stem Cells: Implications for Stroke Treatment" @default.
- W2747492066 cites W1484379838 @default.
- W2747492066 cites W1515821766 @default.
- W2747492066 cites W1545991729 @default.
- W2747492066 cites W1590831986 @default.
- W2747492066 cites W1756074693 @default.
- W2747492066 cites W1766509663 @default.
- W2747492066 cites W1874035916 @default.
- W2747492066 cites W1923630585 @default.
- W2747492066 cites W1976630254 @default.
- W2747492066 cites W1977450644 @default.
- W2747492066 cites W1980621373 @default.
- W2747492066 cites W1981292931 @default.
- W2747492066 cites W1982373471 @default.
- W2747492066 cites W1984200978 @default.
- W2747492066 cites W1993845966 @default.
- W2747492066 cites W1999662797 @default.
- W2747492066 cites W1999783884 @default.
- W2747492066 cites W2002794817 @default.
- W2747492066 cites W2002815598 @default.
- W2747492066 cites W2004120209 @default.
- W2747492066 cites W2007242343 @default.
- W2747492066 cites W2007543609 @default.
- W2747492066 cites W2007883639 @default.
- W2747492066 cites W2009703235 @default.
- W2747492066 cites W2009917542 @default.
- W2747492066 cites W2009933155 @default.
- W2747492066 cites W2014882299 @default.
- W2747492066 cites W2018846024 @default.
- W2747492066 cites W2020554367 @default.
- W2747492066 cites W2020697027 @default.
- W2747492066 cites W2022260373 @default.
- W2747492066 cites W2027726297 @default.
- W2747492066 cites W2029891393 @default.
- W2747492066 cites W2032227357 @default.
- W2747492066 cites W2034722311 @default.
- W2747492066 cites W2039708097 @default.
- W2747492066 cites W2041636719 @default.
- W2747492066 cites W2043254359 @default.
- W2747492066 cites W2044695442 @default.
- W2747492066 cites W2048599333 @default.
- W2747492066 cites W2058034503 @default.
- W2747492066 cites W2058180357 @default.
- W2747492066 cites W2058269456 @default.
- W2747492066 cites W2058399959 @default.
- W2747492066 cites W2059952612 @default.
- W2747492066 cites W2060393760 @default.
- W2747492066 cites W2062229457 @default.
- W2747492066 cites W2062595499 @default.
- W2747492066 cites W2066553255 @default.
- W2747492066 cites W2067335193 @default.
- W2747492066 cites W2072744730 @default.
- W2747492066 cites W2079191966 @default.
- W2747492066 cites W2079407968 @default.
- W2747492066 cites W2080160572 @default.
- W2747492066 cites W2090788868 @default.
- W2747492066 cites W2091798242 @default.
- W2747492066 cites W2094406397 @default.
- W2747492066 cites W2094711438 @default.
- W2747492066 cites W2096907673 @default.
- W2747492066 cites W2103461384 @default.
- W2747492066 cites W2104183007 @default.
- W2747492066 cites W2105433247 @default.
- W2747492066 cites W2110387103 @default.
- W2747492066 cites W2114044744 @default.
- W2747492066 cites W2119542322 @default.
- W2747492066 cites W2121589451 @default.
- W2747492066 cites W2125115491 @default.
- W2747492066 cites W2128555254 @default.
- W2747492066 cites W2136863044 @default.
- W2747492066 cites W2139516275 @default.
- W2747492066 cites W2139621750 @default.
- W2747492066 cites W2143729276 @default.
- W2747492066 cites W2151752675 @default.
- W2747492066 cites W2152546971 @default.
- W2747492066 cites W2153790680 @default.
- W2747492066 cites W2169093550 @default.
- W2747492066 cites W2171058244 @default.
- W2747492066 cites W2176412441 @default.
- W2747492066 cites W2177788064 @default.
- W2747492066 cites W2200533371 @default.
- W2747492066 cites W2257110476 @default.
- W2747492066 cites W2268619028 @default.
- W2747492066 cites W2275153700 @default.
- W2747492066 cites W2283815755 @default.
- W2747492066 cites W2299928089 @default.
- W2747492066 cites W2311740292 @default.
- W2747492066 cites W2318872620 @default.
- W2747492066 cites W2320272319 @default.
- W2747492066 cites W2321304109 @default.
- W2747492066 cites W2325305253 @default.
- W2747492066 cites W2329049508 @default.