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• W2747535265 abstract "Background . Obesity exacerbates age-related decline in glucometabolic control. Undercarboxylated osteocalcin (UcOC) regulates pancreatic insulin secretion. The long-term effect of lifestyle interventions on UcOC and insulin secretion has not been investigated. Methods . One hundred seven frail, obese older adults were randomized into the control (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mi>N</mml:mi><mml:mo>=</mml:mo><mml:mn>27</mml:mn></mml:math>), diet (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mi>N</mml:mi><mml:mo>=</mml:mo><mml:mn>26</mml:mn></mml:math>), exercise (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mi>N</mml:mi><mml:mo>=</mml:mo><mml:mn>26</mml:mn></mml:math>), and diet-exercise (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mi>N</mml:mi><mml:mo>=</mml:mo><mml:mn>28</mml:mn></mml:math>) groups for 1 year. Main outcomes included changes in UcOC and disposition index (DI). Results . UcOC increased in the diet group (36 ± 11.6%) but not in the other groups (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M5><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:math> between groups). Although similar increases in DI occurred in the diet-exercise and diet groups at 6 months, DI increased more in the diet-exercise group (92.4 ± 11.4%) than in the diet group (61.9 ± 15.3%) at 12 months (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M6><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:math>). UcOC and body composition changes predicted DI variation in the diet group only (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M7><mml:msup><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msup><mml:mo>=</mml:mo><mml:mn>0.712</mml:mn></mml:math>), while adipocytokines and physical function changes contributed to DI variation in both the diet (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M8><mml:mo>∆</mml:mo><mml:msup><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msup><mml:mo>=</mml:mo><mml:mn>0.140</mml:mn></mml:math> and 0.107) and diet-exercise (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M9><mml:mo>∆</mml:mo><mml:msup><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msup><mml:mo>=</mml:mo><mml:mn>0.427</mml:mn></mml:math> and 0.243) groups (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M10><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:math> for all). Conclusions . Diet, but not exercise or both, increases UcOC, whereas both diet and diet-exercise increase DI. UcOC accounts for DI variation only during active weight loss, while adipocytokines and physical function contribute to diet-exercise-induced DI variation, highlighting different mechanisms for lifestyle-induced improvements in insulin secretion. This trial was registered with ClinicalTrials.gov number NCT00146107 ." @default.
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• W2747535265 date "2017-01-01" @default.
• W2747535265 modified "2023-10-15" @default.
• W2747535265 title "Effect of Weight Loss, Exercise, or Both on Undercarboxylated Osteocalcin and Insulin Secretion in Frail, Obese Older Adults" @default.
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• W2747535265 cites W2003401249 @default.
• W2747535265 cites W2004860521 @default.
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• W2747535265 cites W2015050458 @default.
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• W2747535265 cites W2061309116 @default.
• W2747535265 cites W2065590498 @default.
• W2747535265 cites W2067741037 @default.
• W2747535265 cites W2075355954 @default.
• W2747535265 cites W2082129124 @default.
• W2747535265 cites W2103160901 @default.
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• W2747535265 cites W2154496298 @default.
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• W2747535265 doi "https://doi.org/10.1155/2017/4807046" @default.
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