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• W2747563144 abstract "Purpose The optimal treatment of patients with choroid plexus carcinoma (CPC) is unclear. We conducted a systematic review and meta-analysis of individual patient information to determine the effect of surgery, adjuvant therapy, and other prognostic factors for CPC. Methods and Materials A comprehensive search of the PubMed and Google Scholar databases was performed using the following MeSH terms to find all possible reports on CPC: choroid plexus tumor; choroid plexus carcinoma; choroid plexus carcinoma AND treatment; and choroid plexus carcinoma AND survival. We performed an individual patient data analysis to assess the strength of the potential associations between different variables and the outcomes for patients with CPC. Results Data from 284 patients were retrieved from 89 studies. The median patient age was 2 years, with 26% patients diagnosed in the first year of their life. Of these 284 patients, 52.8% had undergone gross total resection (GTR) or near total resection. The median follow-up period for the entire cohort was 10.8 months. The median progression-free survival (PFS) was 13 months (95% confidence interval 8.14-17.8). PFS was better for patients >aged 5 years and those who had undergone GTR. The median overall survival (OS) was 29 months (95% confidence interval 16.3-41.7). OS was better for patients aged >5 years, those who had undergone GTR, those who had received adjuvant treatment, and those with a parenchymal tumor site. Conclusions CPC is an aggressive tumor, with a median PFS of 13 months and median OS of 29 months. All patients should undergo maximal safe resection, because GTR is associated with improved survival. The use of adjuvant radiation and chemotherapy were also associated with improved outcomes. The optimal treatment of patients with choroid plexus carcinoma (CPC) is unclear. We conducted a systematic review and meta-analysis of individual patient information to determine the effect of surgery, adjuvant therapy, and other prognostic factors for CPC. A comprehensive search of the PubMed and Google Scholar databases was performed using the following MeSH terms to find all possible reports on CPC: choroid plexus tumor; choroid plexus carcinoma; choroid plexus carcinoma AND treatment; and choroid plexus carcinoma AND survival. We performed an individual patient data analysis to assess the strength of the potential associations between different variables and the outcomes for patients with CPC. Data from 284 patients were retrieved from 89 studies. The median patient age was 2 years, with 26% patients diagnosed in the first year of their life. Of these 284 patients, 52.8% had undergone gross total resection (GTR) or near total resection. The median follow-up period for the entire cohort was 10.8 months. The median progression-free survival (PFS) was 13 months (95% confidence interval 8.14-17.8). PFS was better for patients >aged 5 years and those who had undergone GTR. The median overall survival (OS) was 29 months (95% confidence interval 16.3-41.7). OS was better for patients aged >5 years, those who had undergone GTR, those who had received adjuvant treatment, and those with a parenchymal tumor site. CPC is an aggressive tumor, with a median PFS of 13 months and median OS of 29 months. All patients should undergo maximal safe resection, because GTR is associated with improved survival. The use of adjuvant radiation and chemotherapy were also associated with improved outcomes." @default.
• W2747563144 created "2017-08-31" @default.
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• W2747563144 date "2017-12-01" @default.
• W2747563144 modified "2023-10-16" @default.
• W2747563144 title "Effect of Surgery, Adjuvant Therapy, and Other Prognostic Factors on Choroid Plexus Carcinoma: A Systematic Review and Individual Patient Data Analysis" @default.
• W2747563144 cites W1070685334 @default.
• W2747563144 cites W1438430462 @default.
• W2747563144 cites W1481216330 @default.
• W2747563144 cites W155502479 @default.
• W2747563144 cites W1560482859 @default.
• W2747563144 cites W1580450252 @default.
• W2747563144 cites W1630995793 @default.
• W2747563144 cites W1966572972 @default.
• W2747563144 cites W1967197214 @default.
• W2747563144 cites W1967207164 @default.
• W2747563144 cites W1967530657 @default.
• W2747563144 cites W1967952174 @default.
• W2747563144 cites W1969506590 @default.
• W2747563144 cites W1971326361 @default.
• W2747563144 cites W1973024068 @default.
• W2747563144 cites W1973492865 @default.
• W2747563144 cites W1973965861 @default.
• W2747563144 cites W1974897606 @default.
• W2747563144 cites W1976402042 @default.
• W2747563144 cites W1984281462 @default.
• W2747563144 cites W1989213743 @default.
• W2747563144 cites W1994972088 @default.
• W2747563144 cites W1997355458 @default.
• W2747563144 cites W1998962618 @default.
• W2747563144 cites W2001158604 @default.
• W2747563144 cites W2002993576 @default.
• W2747563144 cites W2004144447 @default.
• W2747563144 cites W2004901627 @default.
• W2747563144 cites W2005844848 @default.
• W2747563144 cites W2012817482 @default.
• W2747563144 cites W2016861541 @default.
• W2747563144 cites W2022995075 @default.
• W2747563144 cites W2025233277 @default.
• W2747563144 cites W2027030412 @default.
• W2747563144 cites W2033175243 @default.
• W2747563144 cites W2033635017 @default.
• W2747563144 cites W2037007312 @default.
• W2747563144 cites W2039329678 @default.
• W2747563144 cites W2039738556 @default.
• W2747563144 cites W2043207250 @default.
• W2747563144 cites W2050609409 @default.
• W2747563144 cites W2051117645 @default.
• W2747563144 cites W2052209235 @default.
• W2747563144 cites W2052428521 @default.
• W2747563144 cites W2053417714 @default.
• W2747563144 cites W2055499585 @default.
• W2747563144 cites W2055824324 @default.
• W2747563144 cites W2061857859 @default.
• W2747563144 cites W2065047770 @default.
• W2747563144 cites W2065122489 @default.
• W2747563144 cites W2065419640 @default.
• W2747563144 cites W2067098690 @default.
• W2747563144 cites W2070084730 @default.
• W2747563144 cites W2071140602 @default.
• W2747563144 cites W2075490255 @default.
• W2747563144 cites W2078041675 @default.
• W2747563144 cites W2078953732 @default.
• W2747563144 cites W2081281249 @default.
• W2747563144 cites W2082664913 @default.
• W2747563144 cites W2083602692 @default.
• W2747563144 cites W2085465865 @default.
• W2747563144 cites W2088189850 @default.
• W2747563144 cites W2090129677 @default.
• W2747563144 cites W2090484402 @default.
• W2747563144 cites W2116121536 @default.
• W2747563144 cites W2117878711 @default.
• W2747563144 cites W2118980621 @default.
• W2747563144 cites W2131985358 @default.
• W2747563144 cites W2135602196 @default.
• W2747563144 cites W2138421655 @default.
• W2747563144 cites W2156196555 @default.
• W2747563144 cites W2159855351 @default.
• W2747563144 cites W2160702645 @default.
• W2747563144 cites W2166804439 @default.
• W2747563144 cites W2166893367 @default.
• W2747563144 cites W2177715817 @default.
• W2747563144 cites W2295734225 @default.
• W2747563144 cites W2334878392 @default.
• W2747563144 cites W2366536035 @default.
• W2747563144 cites W2400583765 @default.
• W2747563144 cites W2416015809 @default.
• W2747563144 cites W4293529598 @default.
• W2747563144 cites W70153828 @default.
• W2747563144 cites W999894669 @default.
• W2747563144 doi "https://doi.org/10.1016/j.ijrobp.2017.08.012" @default.
• W2747563144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28939225" @default.
• W2747563144 hasPublicationYear "2017" @default.
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