FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2748014562> ?p ?o ?g. }

• W2748014562 endingPage "e0184010" @default.
• W2748014562 startingPage "e0184010" @default.
• W2748014562 abstract "Paracoccidioides brasiliensis yeast was reported to express paracoccin, a GlcNAc-binding protein that displays N-acetyl-β-d-glucosaminidase (NAGase) activity. Highly specific anti-paracoccin antibodies have been previously used to examine the localization of paracoccin in yeast and inhibit its growth in vitro. In the present study, anti-paracoccin antibodies were used to characterize, by scanning confocal microscopy, the distribution of paracoccin in P. brasiliensis hyphae, transition forms from hyphae to yeast, and mature yeast. In the mycelial phase, paracoccin was detected mainly in the hyphae tips, where it demonstrated a punctate distribution, and was associated with the cell wall. During the first 48 hours after a temperature shift from 26°C to 37°C, paracoccin expression in the differentiating hyphae was mainly detected in the budding regions, i.e. lateral protrusions, and inside the new daughter cells. There was an increased number of chlamydoconidia that expressed a high concentration of paracoccin on their surfaces and/or in their interiors 72-96 hours after the temperature shift. After 120 hours, yeast cells were the predominant form and their cytoplasm stained extensively for paracoccin, whereas Wheat Germ Agglutinin (WGA) staining was predominant on their exterior walls. After 10 days at 37°C, the interior of both mother and daughter yeast cells, as well as the budding regions, stained intensely for paracoccin. The comparison of mRNA-expression in the different fungal forms showed that PCN transcripts, although detected in all evaluated morphological forms, were higher in hypha and yeast-to-hypha transition forms. In conclusion, the pattern of paracoccin distribution in all P. brasiliensis morphotypes supports prevalent beliefs that it plays important roles in fungal growth and dimorphic transformation." @default.
• W2748014562 created "2017-08-31" @default.
• W2748014562 creator A5010866579 @default.
• W2748014562 creator A5019269365 @default.
• W2748014562 creator A5019294126 @default.
• W2748014562 creator A5021960320 @default.
• W2748014562 creator A5023022791 @default.
• W2748014562 creator A5038097724 @default.
• W2748014562 creator A5066964916 @default.
• W2748014562 creator A5079424307 @default.
• W2748014562 creator A5080859448 @default.
• W2748014562 date "2017-08-28" @default.
• W2748014562 modified "2023-10-02" @default.
• W2748014562 title "Paracoccin distribution supports its role in Paracoccidioides brasiliensis growth and dimorphic transformation" @default.
• W2748014562 cites W1537152227 @default.
• W2748014562 cites W1553773316 @default.
• W2748014562 cites W1593423519 @default.
• W2748014562 cites W1643685414 @default.
• W2748014562 cites W1646189357 @default.
• W2748014562 cites W1809112691 @default.
• W2748014562 cites W1892375640 @default.
• W2748014562 cites W1955881849 @default.
• W2748014562 cites W1982819041 @default.
• W2748014562 cites W1994734142 @default.
• W2748014562 cites W1996179662 @default.
• W2748014562 cites W1997437177 @default.
• W2748014562 cites W2000066478 @default.
• W2748014562 cites W2000070221 @default.
• W2748014562 cites W2002940694 @default.
• W2748014562 cites W2004580747 @default.
• W2748014562 cites W2012991384 @default.
• W2748014562 cites W2014732005 @default.
• W2748014562 cites W2036665353 @default.
• W2748014562 cites W2041050865 @default.
• W2748014562 cites W2044491260 @default.
• W2748014562 cites W2058481690 @default.
• W2748014562 cites W2065628251 @default.
• W2748014562 cites W2102526806 @default.
• W2748014562 cites W2106158762 @default.
• W2748014562 cites W2113224630 @default.
• W2748014562 cites W2122348402 @default.
• W2748014562 cites W2129334012 @default.
• W2748014562 cites W2132928249 @default.
• W2748014562 cites W2138499238 @default.
• W2748014562 cites W2144099115 @default.
• W2748014562 cites W2147994140 @default.
• W2748014562 cites W2152618345 @default.
• W2748014562 cites W2152832189 @default.
• W2748014562 cites W2153621189 @default.
• W2748014562 cites W2158574346 @default.
• W2748014562 cites W2160085634 @default.
• W2748014562 cites W2160387352 @default.
• W2748014562 cites W2160451426 @default.
• W2748014562 cites W2170802564 @default.
• W2748014562 cites W2396435701 @default.
• W2748014562 cites W2408929886 @default.
• W2748014562 cites W2738401853 @default.
• W2748014562 doi "https://doi.org/10.1371/journal.pone.0184010" @default.
• W2748014562 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5573292" @default.
• W2748014562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28846733" @default.
• W2748014562 hasPublicationYear "2017" @default.
• W2748014562 type Work @default.
• W2748014562 sameAs 2748014562 @default.
• W2748014562 citedByCount "3" @default.
• W2748014562 countsByYear W27480145622017 @default.
• W2748014562 countsByYear W27480145622019 @default.
• W2748014562 countsByYear W27480145622021 @default.
• W2748014562 crossrefType "journal-article" @default.
• W2748014562 hasAuthorship W2748014562A5010866579 @default.
• W2748014562 hasAuthorship W2748014562A5019269365 @default.
• W2748014562 hasAuthorship W2748014562A5019294126 @default.
• W2748014562 hasAuthorship W2748014562A5021960320 @default.
• W2748014562 hasAuthorship W2748014562A5023022791 @default.
• W2748014562 hasAuthorship W2748014562A5038097724 @default.
• W2748014562 hasAuthorship W2748014562A5066964916 @default.
• W2748014562 hasAuthorship W2748014562A5079424307 @default.
• W2748014562 hasAuthorship W2748014562A5080859448 @default.
• W2748014562 hasBestOaLocation W27480145621 @default.
• W2748014562 hasConcept C125235067 @default.
• W2748014562 hasConcept C133479454 @default.
• W2748014562 hasConcept C153911025 @default.
• W2748014562 hasConcept C190062978 @default.
• W2748014562 hasConcept C198410946 @default.
• W2748014562 hasConcept C21717790 @default.
• W2748014562 hasConcept C2777681368 @default.
• W2748014562 hasConcept C2779108831 @default.
• W2748014562 hasConcept C2779222958 @default.
• W2748014562 hasConcept C2909986799 @default.
• W2748014562 hasConcept C36755584 @default.
• W2748014562 hasConcept C54355233 @default.
• W2748014562 hasConcept C55493867 @default.
• W2748014562 hasConcept C59822182 @default.
• W2748014562 hasConcept C74864618 @default.
• W2748014562 hasConcept C86803240 @default.
• W2748014562 hasConcept C89423630 @default.
• W2748014562 hasConcept C90080823 @default.
• W2748014562 hasConcept C95444343 @default.
• W2748014562 hasConceptScore W2748014562C125235067 @default.

• next