FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2748088957> ?p ?o ?g. }

• W2748088957 endingPage "547" @default.
• W2748088957 startingPage "537" @default.
• W2748088957 abstract "Financial capacity (FC) is a cognitively complex activity of daily living that declines in mild cognitive impairment (MCI) and Alzheimer's disease (AD), limiting an individual's ability to manage one's finances and function independently. The neural underpinnings of this decline in function are poorly understood but likely involve age-related and disease-related degradation across structural networks. The purpose of the current study was to determine if altered white matter integrity is associated with declining FC in persons with MCI and AD compared to older controls. Individuals with MCI due to AD (n = 31), mild dementia (n = 39), and cognitively healthy older adults (n = 60) were administered a neuropsychological battery including the FC Instrument, a performance-based measure of FC. All 130 participants also underwent diffusion tensor imaging (DTI) upon which tract-based spatial statistics were performed. Both FC and white matter integrity decreased in accordance with disease severity with little to no effect in healthy elderly, significant effects in MCI, and greater effects in AD. Regional white matter degradation (increased diffusivities and decreased fractional anisotropy) was associated with reduced FC in both MCI and AD groups even after controlling for age, education, and gender. Specifically, in MCI, decreased fractional anisotropy, but not increased diffusivities, was associated with poorer FC in widespread cingulo-parietal-frontal and temporo-occipital areas. In AD, rather than anisotropy, increased mean and axial diffusivities in anterior cingulate, callosum, and frontal areas associated with poorer FC. These findings suggest a severity gradient of white matter degradation across DTI metrics and AD stages that predict declining financial skill and knowledge." @default.
• W2748088957 created "2017-08-31" @default.
• W2748088957 creator A5002713023 @default.
• W2748088957 creator A5051058343 @default.
• W2748088957 creator A5078646190 @default.
• W2748088957 creator A5089935579 @default.
• W2748088957 date "2017-09-18" @default.
• W2748088957 modified "2023-09-29" @default.
• W2748088957 title "White Matter Degradation is Associated with Reduced Financial Capacity in Mild Cognitive Impairment and Alzheimer’s Disease" @default.
• W2748088957 cites W1535222849 @default.
• W2748088957 cites W157163224 @default.
• W2748088957 cites W1847168837 @default.
• W2748088957 cites W1977103876 @default.
• W2748088957 cites W1983865126 @default.
• W2748088957 cites W1984167936 @default.
• W2748088957 cites W1991755427 @default.
• W2748088957 cites W1991952617 @default.
• W2748088957 cites W1993643554 @default.
• W2748088957 cites W1994972002 @default.
• W2748088957 cites W2002192979 @default.
• W2748088957 cites W2008854521 @default.
• W2748088957 cites W2011235224 @default.
• W2748088957 cites W2028748733 @default.
• W2748088957 cites W2046557060 @default.
• W2748088957 cites W2050645001 @default.
• W2748088957 cites W2058161128 @default.
• W2748088957 cites W2059412836 @default.
• W2748088957 cites W2066429484 @default.
• W2748088957 cites W2067240723 @default.
• W2748088957 cites W2071881327 @default.
• W2748088957 cites W2073516918 @default.
• W2748088957 cites W2073850739 @default.
• W2748088957 cites W2087816081 @default.
• W2748088957 cites W2092497652 @default.
• W2748088957 cites W2093650784 @default.
• W2748088957 cites W2094016424 @default.
• W2748088957 cites W2107169104 @default.
• W2748088957 cites W2110431535 @default.
• W2748088957 cites W2113708991 @default.
• W2748088957 cites W2115017507 @default.
• W2748088957 cites W2120265621 @default.
• W2748088957 cites W2123261378 @default.
• W2748088957 cites W2126080113 @default.
• W2748088957 cites W2126693856 @default.
• W2748088957 cites W2134248637 @default.
• W2748088957 cites W2140629943 @default.
• W2748088957 cites W2141928661 @default.
• W2748088957 cites W2148080316 @default.
• W2748088957 cites W2150667092 @default.
• W2748088957 cites W2156220037 @default.
• W2748088957 cites W2157035009 @default.
• W2748088957 cites W2160917765 @default.
• W2748088957 cites W2162723250 @default.
• W2748088957 cites W2167311298 @default.
• W2748088957 cites W2168844688 @default.
• W2748088957 cites W2169499022 @default.
• W2748088957 cites W2274803008 @default.
• W2748088957 cites W2420611136 @default.
• W2748088957 cites W2582524520 @default.
• W2748088957 cites W2602102616 @default.
• W2748088957 cites W2977883299 @default.
• W2748088957 doi "https://doi.org/10.3233/jad-170341" @default.
• W2748088957 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5642279" @default.
• W2748088957 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28826185" @default.
• W2748088957 hasPublicationYear "2017" @default.
• W2748088957 type Work @default.
• W2748088957 sameAs 2748088957 @default.
• W2748088957 citedByCount "12" @default.
• W2748088957 countsByYear W27480889572019 @default.
• W2748088957 countsByYear W27480889572020 @default.
• W2748088957 countsByYear W27480889572021 @default.
• W2748088957 countsByYear W27480889572022 @default.
• W2748088957 countsByYear W27480889572023 @default.
• W2748088957 crossrefType "journal-article" @default.
• W2748088957 hasAuthorship W2748088957A5002713023 @default.
• W2748088957 hasAuthorship W2748088957A5051058343 @default.
• W2748088957 hasAuthorship W2748088957A5078646190 @default.
• W2748088957 hasAuthorship W2748088957A5089935579 @default.
• W2748088957 hasBestOaLocation W27480889572 @default.
• W2748088957 hasConcept C126322002 @default.
• W2748088957 hasConcept C126838900 @default.
• W2748088957 hasConcept C14216870 @default.
• W2748088957 hasConcept C143409427 @default.
• W2748088957 hasConcept C149550507 @default.
• W2748088957 hasConcept C15744967 @default.
• W2748088957 hasConcept C164705383 @default.
• W2748088957 hasConcept C169760540 @default.
• W2748088957 hasConcept C169900460 @default.
• W2748088957 hasConcept C2778183499 @default.
• W2748088957 hasConcept C2779134260 @default.
• W2748088957 hasConcept C2779483572 @default.
• W2748088957 hasConcept C2781192897 @default.
• W2748088957 hasConcept C502032728 @default.
• W2748088957 hasConcept C548259974 @default.
• W2748088957 hasConcept C71924100 @default.
• W2748088957 hasConcept C89916169 @default.
• W2748088957 hasConceptScore W2748088957C126322002 @default.
• W2748088957 hasConceptScore W2748088957C126838900 @default.

• next