FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2748188081> ?p ?o ?g. }

• W2748188081 abstract "Abstract Asymmetric cell divisions are of fundamental importance for the development of multicellular organisms, e.g. for the generation of founder cells. Prime examples are asymmetric cell divisions in germline precursors during the early embryogenesis of the transparent roundworm Caenorhabditis elegans , one of the major developmental model organisms. However, due to a lack of quantitative data it has remained unclear how frequent unequal daughter cell sizes emerge in the worm’s early embryogenesis, and whether these originate from sterical or biochemical cues. Using quantitative light-sheet microscopy, we have found that about 40% of all cell divisions in C. elegans until gastrulation generate daughter cells with significantly different volumes. Removing the embryo’s rigid eggshell revealed asymmetric divisions in somatic cells to be primarily induced by steric effects. Division asymmetries in the germline remained unaltered and were correctly reproduced by a model based on a cell-size independent, eccentric displacement of the metaphase plate. Our data suggest that asymmetric cell divisions, imposed by physical determinants, are essential for establishing important cell-cell interactions that eventually fuel a successful embryogenesis." @default.
• W2748188081 created "2017-08-31" @default.
• W2748188081 creator A5050264123 @default.
• W2748188081 creator A5054742160 @default.
• W2748188081 date "2017-08-24" @default.
• W2748188081 modified "2023-09-25" @default.
• W2748188081 title "Physical determinants of asymmetric cell divisions in the early development of Caenorhabditis elegans" @default.
• W2748188081 cites W1854688115 @default.
• W2748188081 cites W1975022818 @default.
• W2748188081 cites W1976010237 @default.
• W2748188081 cites W1979762239 @default.
• W2748188081 cites W1989952069 @default.
• W2748188081 cites W1997275744 @default.
• W2748188081 cites W2000929749 @default.
• W2748188081 cites W2007496445 @default.
• W2748188081 cites W2017951283 @default.
• W2748188081 cites W2019365008 @default.
• W2748188081 cites W2028945975 @default.
• W2748188081 cites W2033584644 @default.
• W2748188081 cites W2037486322 @default.
• W2748188081 cites W2045177215 @default.
• W2748188081 cites W2052225357 @default.
• W2748188081 cites W2052611780 @default.
• W2748188081 cites W2054352933 @default.
• W2748188081 cites W2068920904 @default.
• W2748188081 cites W2071439887 @default.
• W2748188081 cites W2086819694 @default.
• W2748188081 cites W2094643072 @default.
• W2748188081 cites W2097664711 @default.
• W2748188081 cites W2126306109 @default.
• W2748188081 cites W2136535147 @default.
• W2748188081 cites W2137794042 @default.
• W2748188081 cites W2159466932 @default.
• W2748188081 cites W2186611144 @default.
• W2748188081 cites W2233150933 @default.
• W2748188081 cites W2253629570 @default.
• W2748188081 cites W2415545601 @default.
• W2748188081 cites W2536506179 @default.
• W2748188081 cites W4300901678 @default.
• W2748188081 doi "https://doi.org/10.1038/s41598-017-09690-4" @default.
• W2748188081 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5571195" @default.
• W2748188081 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28839200" @default.
• W2748188081 hasPublicationYear "2017" @default.
• W2748188081 type Work @default.
• W2748188081 sameAs 2748188081 @default.
• W2748188081 citedByCount "19" @default.
• W2748188081 countsByYear W27481880812018 @default.
• W2748188081 countsByYear W27481880812019 @default.
• W2748188081 countsByYear W27481880812020 @default.
• W2748188081 countsByYear W27481880812021 @default.
• W2748188081 countsByYear W27481880812022 @default.
• W2748188081 countsByYear W27481880812023 @default.
• W2748188081 crossrefType "journal-article" @default.
• W2748188081 hasAuthorship W2748188081A5050264123 @default.
• W2748188081 hasAuthorship W2748188081A5054742160 @default.
• W2748188081 hasBestOaLocation W27481880811 @default.
• W2748188081 hasConcept C104317684 @default.
• W2748188081 hasConcept C109825262 @default.
• W2748188081 hasConcept C129536746 @default.
• W2748188081 hasConcept C134305767 @default.
• W2748188081 hasConcept C1491633281 @default.
• W2748188081 hasConcept C163952510 @default.
• W2748188081 hasConcept C196843134 @default.
• W2748188081 hasConcept C19843653 @default.
• W2748188081 hasConcept C2778944004 @default.
• W2748188081 hasConcept C2778977658 @default.
• W2748188081 hasConcept C45472230 @default.
• W2748188081 hasConcept C54355233 @default.
• W2748188081 hasConcept C62112901 @default.
• W2748188081 hasConcept C74318829 @default.
• W2748188081 hasConcept C85813293 @default.
• W2748188081 hasConcept C86339819 @default.
• W2748188081 hasConcept C86803240 @default.
• W2748188081 hasConcept C87073359 @default.
• W2748188081 hasConcept C95444343 @default.
• W2748188081 hasConceptScore W2748188081C104317684 @default.
• W2748188081 hasConceptScore W2748188081C109825262 @default.
• W2748188081 hasConceptScore W2748188081C129536746 @default.
• W2748188081 hasConceptScore W2748188081C134305767 @default.
• W2748188081 hasConceptScore W2748188081C1491633281 @default.
• W2748188081 hasConceptScore W2748188081C163952510 @default.
• W2748188081 hasConceptScore W2748188081C196843134 @default.
• W2748188081 hasConceptScore W2748188081C19843653 @default.
• W2748188081 hasConceptScore W2748188081C2778944004 @default.
• W2748188081 hasConceptScore W2748188081C2778977658 @default.
• W2748188081 hasConceptScore W2748188081C45472230 @default.
• W2748188081 hasConceptScore W2748188081C54355233 @default.
• W2748188081 hasConceptScore W2748188081C62112901 @default.
• W2748188081 hasConceptScore W2748188081C74318829 @default.
• W2748188081 hasConceptScore W2748188081C85813293 @default.
• W2748188081 hasConceptScore W2748188081C86339819 @default.
• W2748188081 hasConceptScore W2748188081C86803240 @default.
• W2748188081 hasConceptScore W2748188081C87073359 @default.
• W2748188081 hasConceptScore W2748188081C95444343 @default.
• W2748188081 hasIssue "1" @default.
• W2748188081 hasLocation W27481880811 @default.
• W2748188081 hasLocation W27481880812 @default.
• W2748188081 hasLocation W27481880813 @default.
• W2748188081 hasLocation W27481880814 @default.
• W2748188081 hasLocation W27481880815 @default.

• next