Matches in SemOpenAlex for { <https://semopenalex.org/work/W2748412033> ?p ?o ?g. }
- W2748412033 endingPage "324" @default.
- W2748412033 startingPage "324" @default.
- W2748412033 abstract "Sepsis is one of the major challenges of today. Although gram-positive bacteria related infections are more prevalent in hospital setting, the highest mortality rate is associated with gram-negative microorganisms especially Enterobacteriaceae. Enterobacteriaceae, including Escherichia coli, Klebsiella spp., Proteus spp., Enterobacter spp. and Serratia spp. Resistance to β-lactams in Enterobacteriaceae is primarily attributed to the production of B-lactamase enzymes with subsequent antibiotic hydrolysis and to a lesser extent by alteration of efflux pump or porins expression. Carbapenem resistant Enterobacteriaceae (CRE) and Acinetobacter baumannii are the most notorious pathogens due to the high incidence of morbidity and mortality especially in the immunocompromised patients in the intensive care unit. The most appropriate antimicrobial therapy to treat CRE is still controversial. Combination therapy is preferred over monotherapy due to its broad-spectrum coverage of micro-organisms, due to its synergetic effect and to prevent development of further resistance. Current suggested therapies for CRE resistance as well as promising antibiotics that are currently under investigation for winning the war against the emerging CRE resistance are reviewed and discussed." @default.
- W2748412033 created "2017-08-31" @default.
- W2748412033 creator A5026681312 @default.
- W2748412033 creator A5033790181 @default.
- W2748412033 creator A5037520588 @default.
- W2748412033 creator A5040138721 @default.
- W2748412033 date "2017-01-01" @default.
- W2748412033 modified "2023-10-16" @default.
- W2748412033 title "Treatment of sepsis: What is the antibiotic choice in bacteremia due to carbapenem resistant<i>Enterobacteriaceae</i>?" @default.
- W2748412033 cites W1483646930 @default.
- W2748412033 cites W1612376079 @default.
- W2748412033 cites W1833417126 @default.
- W2748412033 cites W1931389279 @default.
- W2748412033 cites W1985347593 @default.
- W2748412033 cites W1995887867 @default.
- W2748412033 cites W2021439166 @default.
- W2748412033 cites W2028051811 @default.
- W2748412033 cites W2028494881 @default.
- W2748412033 cites W2064234844 @default.
- W2748412033 cites W2065337857 @default.
- W2748412033 cites W2073316020 @default.
- W2748412033 cites W2075724672 @default.
- W2748412033 cites W2096382281 @default.
- W2748412033 cites W2099570276 @default.
- W2748412033 cites W2103077615 @default.
- W2748412033 cites W2112203749 @default.
- W2748412033 cites W2117795567 @default.
- W2748412033 cites W2118519564 @default.
- W2748412033 cites W2119680467 @default.
- W2748412033 cites W2122457645 @default.
- W2748412033 cites W2129122982 @default.
- W2748412033 cites W2129326896 @default.
- W2748412033 cites W2129419942 @default.
- W2748412033 cites W2131946678 @default.
- W2748412033 cites W2133406641 @default.
- W2748412033 cites W2141966178 @default.
- W2748412033 cites W2142232742 @default.
- W2748412033 cites W2145041871 @default.
- W2748412033 cites W2145577370 @default.
- W2748412033 cites W2151496242 @default.
- W2748412033 cites W2154281147 @default.
- W2748412033 cites W2164697816 @default.
- W2748412033 cites W2166505398 @default.
- W2748412033 cites W2168856923 @default.
- W2748412033 cites W2171144560 @default.
- W2748412033 cites W2173323543 @default.
- W2748412033 cites W2266932982 @default.
- W2748412033 cites W2277411304 @default.
- W2748412033 cites W2280404143 @default.
- W2748412033 cites W2302268482 @default.
- W2748412033 cites W2325286363 @default.
- W2748412033 cites W2325675302 @default.
- W2748412033 cites W2336621586 @default.
- W2748412033 cites W2396597555 @default.
- W2748412033 cites W2413463682 @default.
- W2748412033 cites W2468793326 @default.
- W2748412033 cites W2482471973 @default.
- W2748412033 cites W2483207560 @default.
- W2748412033 cites W2486556262 @default.
- W2748412033 cites W2514755464 @default.
- W2748412033 cites W2516106496 @default.
- W2748412033 cites W2517923973 @default.
- W2748412033 cites W2548338486 @default.
- W2748412033 cites W2560084689 @default.
- W2748412033 cites W2564273069 @default.
- W2748412033 cites W4245831427 @default.
- W2748412033 doi "https://doi.org/10.12998/wjcc.v5.i8.324" @default.
- W2748412033 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5561501" @default.
- W2748412033 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28868304" @default.
- W2748412033 hasPublicationYear "2017" @default.
- W2748412033 type Work @default.
- W2748412033 sameAs 2748412033 @default.
- W2748412033 citedByCount "21" @default.
- W2748412033 countsByYear W27484120332017 @default.
- W2748412033 countsByYear W27484120332018 @default.
- W2748412033 countsByYear W27484120332019 @default.
- W2748412033 countsByYear W27484120332020 @default.
- W2748412033 countsByYear W27484120332021 @default.
- W2748412033 countsByYear W27484120332022 @default.
- W2748412033 countsByYear W27484120332023 @default.
- W2748412033 crossrefType "journal-article" @default.
- W2748412033 hasAuthorship W2748412033A5026681312 @default.
- W2748412033 hasAuthorship W2748412033A5033790181 @default.
- W2748412033 hasAuthorship W2748412033A5037520588 @default.
- W2748412033 hasAuthorship W2748412033A5040138721 @default.
- W2748412033 hasBestOaLocation W27484120331 @default.
- W2748412033 hasConcept C104317684 @default.
- W2748412033 hasConcept C126322002 @default.
- W2748412033 hasConcept C2775992322 @default.
- W2748412033 hasConcept C2776315533 @default.
- W2748412033 hasConcept C2776450100 @default.
- W2748412033 hasConcept C2776685102 @default.
- W2748412033 hasConcept C2777637488 @default.
- W2748412033 hasConcept C2778384902 @default.
- W2748412033 hasConcept C2778523567 @default.
- W2748412033 hasConcept C2778910516 @default.
- W2748412033 hasConcept C2778983983 @default.
- W2748412033 hasConcept C2779443120 @default.