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- W2748788959 endingPage "779" @default.
- W2748788959 startingPage "770" @default.
- W2748788959 abstract "The neurobiology of psychiatric disorders is still unclear, although changes in multiple neuronal systems, specifically the dopaminergic, glutamatergic, and gamma-aminobutyric acidergic systems as well as abnormalities in synaptic plasticity and neural connectivity, are currently suggested to underlie their pathophysiology. A growing body of evidence suggests multifaceted mitochondrial dysfunction in mental disorders, which is in line with their role in neuronal activity, growth, development, and plasticity. In this review, we describe the main endeavors toward development of treatments that will enhance mitochondrial function and their transition into clinical use in congenital mitochondrial diseases and chronic disorders such as types 1 and 2 diabetes, cardiovascular disorders, and cancer. In addition, we discuss the relevance of mitochondrial targeted treatments to mental disorders and their potential to become a novel therapeutic strategy that will improve the efficiency of the current treatments." @default.
- W2748788959 created "2017-08-31" @default.
- W2748788959 creator A5026241455 @default.
- W2748788959 creator A5071870538 @default.
- W2748788959 date "2018-05-01" @default.
- W2748788959 modified "2023-10-16" @default.
- W2748788959 title "Mitochondrial Targeted Therapies: Where Do We Stand in Mental Disorders?" @default.
- W2748788959 cites W1475272852 @default.
- W2748788959 cites W1493900409 @default.
- W2748788959 cites W1512824421 @default.
- W2748788959 cites W1550986239 @default.
- W2748788959 cites W1589792898 @default.
- W2748788959 cites W1615913434 @default.
- W2748788959 cites W1722845210 @default.
- W2748788959 cites W1820460245 @default.
- W2748788959 cites W1876608137 @default.
- W2748788959 cites W1889656821 @default.
- W2748788959 cites W1938258474 @default.
- W2748788959 cites W1942622409 @default.
- W2748788959 cites W1958192686 @default.
- W2748788959 cites W1964483580 @default.
- W2748788959 cites W1971723295 @default.
- W2748788959 cites W1972011171 @default.
- W2748788959 cites W1973552449 @default.
- W2748788959 cites W1975338314 @default.
- W2748788959 cites W1976180551 @default.
- W2748788959 cites W1976972166 @default.
- W2748788959 cites W1978639395 @default.
- W2748788959 cites W1980482098 @default.
- W2748788959 cites W1982764052 @default.
- W2748788959 cites W1983099105 @default.
- W2748788959 cites W1985367731 @default.
- W2748788959 cites W1986583946 @default.
- W2748788959 cites W1991952977 @default.
- W2748788959 cites W1995069275 @default.
- W2748788959 cites W1995426016 @default.
- W2748788959 cites W1996728254 @default.
- W2748788959 cites W1997086634 @default.
- W2748788959 cites W1997873957 @default.
- W2748788959 cites W1998251890 @default.
- W2748788959 cites W2003064100 @default.
- W2748788959 cites W2005152583 @default.
- W2748788959 cites W2010298389 @default.
- W2748788959 cites W2012309329 @default.
- W2748788959 cites W2019893391 @default.
- W2748788959 cites W2020248575 @default.
- W2748788959 cites W2021909736 @default.
- W2748788959 cites W2022267544 @default.
- W2748788959 cites W2028431915 @default.
- W2748788959 cites W2030637794 @default.
- W2748788959 cites W2031648971 @default.
- W2748788959 cites W2036886147 @default.
- W2748788959 cites W2039717666 @default.
- W2748788959 cites W2040408325 @default.
- W2748788959 cites W2040954238 @default.
- W2748788959 cites W2044320361 @default.
- W2748788959 cites W2046237540 @default.
- W2748788959 cites W2046380842 @default.
- W2748788959 cites W2050434337 @default.
- W2748788959 cites W2053417895 @default.
- W2748788959 cites W2054355568 @default.
- W2748788959 cites W2055172838 @default.
- W2748788959 cites W2055456981 @default.
- W2748788959 cites W2056015556 @default.
- W2748788959 cites W2057713684 @default.
- W2748788959 cites W2058368383 @default.
- W2748788959 cites W2062858947 @default.
- W2748788959 cites W2063755418 @default.
- W2748788959 cites W2063936188 @default.
- W2748788959 cites W2067759289 @default.
- W2748788959 cites W2068119169 @default.
- W2748788959 cites W2070125051 @default.
- W2748788959 cites W2070198207 @default.
- W2748788959 cites W2070774761 @default.
- W2748788959 cites W2074289572 @default.
- W2748788959 cites W2074435125 @default.
- W2748788959 cites W2076229820 @default.
- W2748788959 cites W2081655836 @default.
- W2748788959 cites W2081959933 @default.
- W2748788959 cites W2082921983 @default.
- W2748788959 cites W2084153419 @default.
- W2748788959 cites W2085012452 @default.
- W2748788959 cites W2085106486 @default.
- W2748788959 cites W2085228888 @default.
- W2748788959 cites W2088016850 @default.
- W2748788959 cites W2091391741 @default.
- W2748788959 cites W2098151244 @default.
- W2748788959 cites W2105404724 @default.
- W2748788959 cites W2108977853 @default.
- W2748788959 cites W2110374590 @default.
- W2748788959 cites W2111001861 @default.
- W2748788959 cites W2112299930 @default.
- W2748788959 cites W2112450095 @default.
- W2748788959 cites W2115708356 @default.
- W2748788959 cites W2117830992 @default.
- W2748788959 cites W2118927393 @default.
- W2748788959 cites W2119381641 @default.
- W2748788959 cites W2121186233 @default.