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• W2748844470 abstract "Visceral adiposity index (VAI) is a novel sex-specific index for visceral adipose function; however the association between VAI and hyperuricemia in China is unknown. We aimed to investigate this association, also whether it was independent of metabolic health and obesity phenotypes. 7632 adult subjects from the China Health and Nutrition Survey 2009 were retained. Subjects were categorized into four obesity phenotypes based on a cross-classification of BMI and metabolic health status by two representative criteria. VAI was the best predictors for hyperuricemia irrespective of obesity phenotypes, with area under curve (AUC) ranging 0.665-0.719. The odd ratio (OR) for hyperuricemia in the highest quartile of the VAI were 6.93 (95% CI 5.79-8.29) after adjusting for age and gender. Following further adjustments for metabolic obesity phenotypes and lifestyle confounders, the ORs were 4.88 (3.92-6.09) and 5.65 (4.68-6.82) according to these two criteria, respectively. A similar significant pattern was still found even after adjustment for blood pressure and other cardiovascular risks. Within each metabolic obesity phenotype, the significant association between VAI and hyperuricemia was consistently evident. In conclusion, the association of the VAI with hyperuricemia was significant, especially this association was independent of metabolic health and obesity phenotypes in the Chinese population." @default.
• W2748844470 created "2017-08-31" @default.
• W2748844470 creator A5022943551 @default.
• W2748844470 creator A5032020934 @default.
• W2748844470 creator A5075842385 @default.
• W2748844470 creator A5085592374 @default.
• W2748844470 date "2017-08-18" @default.
• W2748844470 modified "2023-09-30" @default.
• W2748844470 title "Visceral adiposity index is strongly associated with hyperuricemia independently of metabolic health and obesity phenotypes" @default.
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• W2748844470 doi "https://doi.org/10.1038/s41598-017-09455-z" @default.
• W2748844470 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5562916" @default.
• W2748844470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28821853" @default.

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