FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2749078254> ?p ?o ?g. }

• W2749078254 endingPage "E698" @default.
• W2749078254 startingPage "E690" @default.
• W2749078254 abstract "The period around bariatric surgery offers a unique opportunity to characterize metabolism responses to dynamic shifts in energy, gut function, and anesthesia. We analyzed plasma acylcarnitines in obese women ( n = 17) sampled in the overnight fasted/postabsorptive state approximately 1–2 wk before surgery ( condition A), the morning of surgery (prior restriction to a 48-h clear liquid diet coupled in some cases a standard polyethylene glycol gut evacuation: condition B), and following induction of anesthesia ( condition C). Comparisons tested if 1) plasma acylcarnitine derivatives reflective of fatty acid oxidation (FAO) and xenometabolism would be significantly increased and decreased, respectively, by preoperative gut preparation/negative energy balance ( condition A vs. B), and 2) anesthesia would acutely depress markers of FAO. Acylcarnitines associated with fat mobilization and FAO were significantly increased in condition B: long-chain acylcarnitines (i.e., C18:1, ~70%), metabolites from active but incomplete FAO [i.e., C14:1 (161%) and C14:2 (102%)] and medium- to short-chain acylcarnitines [i.e., C2 (91%), R-3-hydroxybutyryl-(245%), C6 (45%), and cis-3,4-methylene-heptanoyl-(17%), etc.]. Branched-chain amino acid markers displayed disparate patterns [i.e., isobutyryl-(40% decreased) vs. isovaleryl carnitine (51% increased)]. Anesthesia reduced virtually every acylcarnitine. These results are consistent with a fasting-type metabolic phenotype coincident with the presurgical “gut preparation” phase of bariatric surgery, and a major and rapid alteration of both fat and amino acid metabolism with onset of anesthesia. Whether presurgical or anesthesia-associated metabolic shifts in carnitine and fuel metabolism impact patient outcomes or surgical risks remains to be evaluated experimentally." @default.
• W2749078254 created "2017-08-31" @default.
• W2749078254 creator A5036117667 @default.
• W2749078254 creator A5036579753 @default.
• W2749078254 creator A5055425420 @default.
• W2749078254 creator A5061461109 @default.
• W2749078254 creator A5061744695 @default.
• W2749078254 creator A5063050485 @default.
• W2749078254 creator A5066470222 @default.
• W2749078254 date "2017-12-01" @default.
• W2749078254 modified "2023-10-15" @default.
• W2749078254 title "Anesthesia and bariatric surgery gut preparation alter plasma acylcarnitines reflective of mitochondrial fat and branched-chain amino acid oxidation" @default.
• W2749078254 cites W122853067 @default.
• W2749078254 cites W1529412398 @default.
• W2749078254 cites W1775915449 @default.
• W2749078254 cites W1969830923 @default.
• W2749078254 cites W1983536185 @default.
• W2749078254 cites W1984021045 @default.
• W2749078254 cites W1995187187 @default.
• W2749078254 cites W1997349469 @default.
• W2749078254 cites W2004949307 @default.
• W2749078254 cites W2006092619 @default.
• W2749078254 cites W2007327578 @default.
• W2749078254 cites W2026169088 @default.
• W2749078254 cites W2031003242 @default.
• W2749078254 cites W2034812606 @default.
• W2749078254 cites W2050778794 @default.
• W2749078254 cites W2050859140 @default.
• W2749078254 cites W2062257015 @default.
• W2749078254 cites W2089356327 @default.
• W2749078254 cites W2098722265 @default.
• W2749078254 cites W2107149602 @default.
• W2749078254 cites W2152007541 @default.
• W2749078254 cites W2179761935 @default.
• W2749078254 cites W2225014908 @default.
• W2749078254 cites W2242613625 @default.
• W2749078254 cites W2244158842 @default.
• W2749078254 cites W2409932196 @default.
• W2749078254 cites W2523406925 @default.
• W2749078254 cites W2531417571 @default.
• W2749078254 cites W4205915111 @default.
• W2749078254 doi "https://doi.org/10.1152/ajpendo.00222.2017" @default.
• W2749078254 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5814600" @default.
• W2749078254 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28830869" @default.
• W2749078254 hasPublicationYear "2017" @default.
• W2749078254 type Work @default.
• W2749078254 sameAs 2749078254 @default.
• W2749078254 citedByCount "5" @default.
• W2749078254 countsByYear W27490782542020 @default.
• W2749078254 countsByYear W27490782542021 @default.
• W2749078254 countsByYear W27490782542022 @default.
• W2749078254 crossrefType "journal-article" @default.
• W2749078254 hasAuthorship W2749078254A5036117667 @default.
• W2749078254 hasAuthorship W2749078254A5036579753 @default.
• W2749078254 hasAuthorship W2749078254A5055425420 @default.
• W2749078254 hasAuthorship W2749078254A5061461109 @default.
• W2749078254 hasAuthorship W2749078254A5061744695 @default.
• W2749078254 hasAuthorship W2749078254A5063050485 @default.
• W2749078254 hasAuthorship W2749078254A5066470222 @default.
• W2749078254 hasBestOaLocation W27490782541 @default.
• W2749078254 hasConcept C126322002 @default.
• W2749078254 hasConcept C134018914 @default.
• W2749078254 hasConcept C185592680 @default.
• W2749078254 hasConcept C19720800 @default.
• W2749078254 hasConcept C2777553358 @default.
• W2749078254 hasConcept C2778435403 @default.
• W2749078254 hasConcept C42219234 @default.
• W2749078254 hasConcept C515207424 @default.
• W2749078254 hasConcept C55493867 @default.
• W2749078254 hasConcept C62231903 @default.
• W2749078254 hasConcept C71924100 @default.
• W2749078254 hasConcept C82714985 @default.
• W2749078254 hasConceptScore W2749078254C126322002 @default.
• W2749078254 hasConceptScore W2749078254C134018914 @default.
• W2749078254 hasConceptScore W2749078254C185592680 @default.
• W2749078254 hasConceptScore W2749078254C19720800 @default.
• W2749078254 hasConceptScore W2749078254C2777553358 @default.
• W2749078254 hasConceptScore W2749078254C2778435403 @default.
• W2749078254 hasConceptScore W2749078254C42219234 @default.
• W2749078254 hasConceptScore W2749078254C515207424 @default.
• W2749078254 hasConceptScore W2749078254C55493867 @default.
• W2749078254 hasConceptScore W2749078254C62231903 @default.
• W2749078254 hasConceptScore W2749078254C71924100 @default.
• W2749078254 hasConceptScore W2749078254C82714985 @default.
• W2749078254 hasFunder F4320337357 @default.
• W2749078254 hasIssue "6" @default.
• W2749078254 hasLocation W27490782541 @default.
• W2749078254 hasLocation W27490782542 @default.
• W2749078254 hasLocation W27490782543 @default.
• W2749078254 hasLocation W27490782544 @default.
• W2749078254 hasOpenAccess W2749078254 @default.
• W2749078254 hasPrimaryLocation W27490782541 @default.
• W2749078254 hasRelatedWork W1553363384 @default.
• W2749078254 hasRelatedWork W1592623275 @default.
• W2749078254 hasRelatedWork W1961710714 @default.
• W2749078254 hasRelatedWork W2036116070 @default.
• W2749078254 hasRelatedWork W2060523002 @default.
• W2749078254 hasRelatedWork W2102326852 @default.

• next