FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2749203596> ?p ?o ?g. }

• W2749203596 endingPage "628" @default.
• W2749203596 startingPage "620" @default.
• W2749203596 abstract "The aim of this study is to assess the effect of repeated injections of dexamethasone implants in patients with persistent diabetic macular edema (DME) despite prior therapies.This retrospective interventional study involved 47 DME-afflicted eyes, which were administered ≥2 intravitreal injections of dexamethasone. Group 1 (34 eyes) received a dexamethasone monotherapy, whereas group 2 (13 eyes) received a combination therapy with intravitreal antivascular endothelial growth factor as needed. The duration of dexamethasone effect until retreatment and the change in best-corrected visual acuity (BCVA) and central retinal thickness (CRT) were defined as outcome measures.A total of 197 injections of dexamethasone were administered in group 1 and 52 in group 2 during a mean follow-up of 23 ± 10 and 24 ± 13 months, respectively. Mean time to reinjection was 4.6 ± 0.5 (group 1) and 5.3 ± 1.0 months (group 2; P = 0.17). Reinjection intervals did not shorten over time for up to 10 dexamethasone injections per eye in group 1 and BCVA improved from before 1 month after the first implantation, 7.0 letters (P = 0.04). In group 2, there was no significant improvement in BCVA at any time point. CRT decreased from 534 ± 208 and 529 ± 215 μm to 287 ± 115 and 371 ± 78 μm at 3 months and increased to 460 ± 186 μm and 547 ± 175 μm before reinjection (groups1 and 2, respectively). The maximal CRT before each implantation remained stable over time.In eyes with chronic DME that respond incompletely to prior therapy or require frequent reinjections, dexamethasone shows promising long-term anatomic and functional improvement. The absence of a treatment effect reduction over time argues against a relevant rebound phenomenon." @default.
• W2749203596 created "2017-08-31" @default.
• W2749203596 creator A5001680107 @default.
• W2749203596 creator A5012927829 @default.
• W2749203596 creator A5014052168 @default.
• W2749203596 creator A5025057269 @default.
• W2749203596 creator A5029499485 @default.
• W2749203596 creator A5031143082 @default.
• W2749203596 creator A5039756423 @default.
• W2749203596 creator A5069786423 @default.
• W2749203596 creator A5075928522 @default.
• W2749203596 date "2017-10-01" @default.
• W2749203596 modified "2023-10-16" @default.
• W2749203596 title "Long-Term Intravitreal Dexamethasone Treatment in Eyes with Pretreated Chronic Diabetic Macular Edema" @default.
• W2749203596 cites W1900258994 @default.
• W2749203596 cites W1964273118 @default.
• W2749203596 cites W1965020544 @default.
• W2749203596 cites W2001352445 @default.
• W2749203596 cites W2004209831 @default.
• W2749203596 cites W2015986808 @default.
• W2749203596 cites W2029869576 @default.
• W2749203596 cites W2038611804 @default.
• W2749203596 cites W2050955343 @default.
• W2749203596 cites W2051133154 @default.
• W2749203596 cites W2061609727 @default.
• W2749203596 cites W2064631491 @default.
• W2749203596 cites W2070438736 @default.
• W2749203596 cites W2088230733 @default.
• W2749203596 cites W2109563236 @default.
• W2749203596 cites W2111540359 @default.
• W2749203596 cites W2123829535 @default.
• W2749203596 cites W2132849987 @default.
• W2749203596 cites W2171946822 @default.
• W2749203596 cites W2314491799 @default.
• W2749203596 cites W2323122966 @default.
• W2749203596 cites W2339854877 @default.
• W2749203596 cites W2425425037 @default.
• W2749203596 cites W2498624319 @default.
• W2749203596 cites W2510267219 @default.
• W2749203596 doi "https://doi.org/10.1089/jop.2017.0020" @default.
• W2749203596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28836880" @default.
• W2749203596 hasPublicationYear "2017" @default.
• W2749203596 type Work @default.
• W2749203596 sameAs 2749203596 @default.
• W2749203596 citedByCount "6" @default.
• W2749203596 countsByYear W27492035962018 @default.
• W2749203596 countsByYear W27492035962019 @default.
• W2749203596 countsByYear W27492035962020 @default.
• W2749203596 countsByYear W27492035962023 @default.
• W2749203596 crossrefType "journal-article" @default.
• W2749203596 hasAuthorship W2749203596A5001680107 @default.
• W2749203596 hasAuthorship W2749203596A5012927829 @default.
• W2749203596 hasAuthorship W2749203596A5014052168 @default.
• W2749203596 hasAuthorship W2749203596A5025057269 @default.
• W2749203596 hasAuthorship W2749203596A5029499485 @default.
• W2749203596 hasAuthorship W2749203596A5031143082 @default.
• W2749203596 hasAuthorship W2749203596A5039756423 @default.
• W2749203596 hasAuthorship W2749203596A5069786423 @default.
• W2749203596 hasAuthorship W2749203596A5075928522 @default.
• W2749203596 hasConcept C118487528 @default.
• W2749203596 hasConcept C126322002 @default.
• W2749203596 hasConcept C134018914 @default.
• W2749203596 hasConcept C141071460 @default.
• W2749203596 hasConcept C2778257484 @default.
• W2749203596 hasConcept C2779829184 @default.
• W2749203596 hasConcept C2780347916 @default.
• W2749203596 hasConcept C2780401358 @default.
• W2749203596 hasConcept C2780886150 @default.
• W2749203596 hasConcept C2985127711 @default.
• W2749203596 hasConcept C555293320 @default.
• W2749203596 hasConcept C71924100 @default.
• W2749203596 hasConceptScore W2749203596C118487528 @default.
• W2749203596 hasConceptScore W2749203596C126322002 @default.
• W2749203596 hasConceptScore W2749203596C134018914 @default.
• W2749203596 hasConceptScore W2749203596C141071460 @default.
• W2749203596 hasConceptScore W2749203596C2778257484 @default.
• W2749203596 hasConceptScore W2749203596C2779829184 @default.
• W2749203596 hasConceptScore W2749203596C2780347916 @default.
• W2749203596 hasConceptScore W2749203596C2780401358 @default.
• W2749203596 hasConceptScore W2749203596C2780886150 @default.
• W2749203596 hasConceptScore W2749203596C2985127711 @default.
• W2749203596 hasConceptScore W2749203596C555293320 @default.
• W2749203596 hasConceptScore W2749203596C71924100 @default.
• W2749203596 hasIssue "8" @default.
• W2749203596 hasLocation W27492035961 @default.
• W2749203596 hasLocation W27492035962 @default.
• W2749203596 hasOpenAccess W2749203596 @default.
• W2749203596 hasPrimaryLocation W27492035961 @default.
• W2749203596 hasRelatedWork W1977181510 @default.
• W2749203596 hasRelatedWork W1988341374 @default.
• W2749203596 hasRelatedWork W2062091766 @default.
• W2749203596 hasRelatedWork W2072671252 @default.
• W2749203596 hasRelatedWork W2942045179 @default.
• W2749203596 hasRelatedWork W3011249866 @default.
• W2749203596 hasRelatedWork W3188338574 @default.
• W2749203596 hasRelatedWork W3202203369 @default.
• W2749203596 hasRelatedWork W37072832 @default.
• W2749203596 hasRelatedWork W4362511091 @default.

• next