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- W27492049 abstract "In rabbit mesenteric arteries, nicotine-evoked vasoconstrictor responses were markedly reduced by prazosin, slightly reduced after desensitization by alpha, beta-methylene ATP, and abolished by combined treatment with prazosin and alpha, beta-methylene ATP. In guinea-pig vasa deferentia preincubated with [3H]noradrenaline, nicotine elicited contractions as well as an overflow of tritium and of ATP. The contractions were greatly reduced by prazosin and abolished after additional desensitization by alpha, beta-methylene ATP. The nicotine-induced overflow of tritium was not changed by either treatment. The overflow of ATP was decreased by prazosin but not diminished further after additional desensitization by alpha, beta-methylene ATP. Activation of prejunctional nicotine receptors elicits a corelease of noradrenaline and ATP which leads to cotransmission in both tissues." @default.
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- W27492049 date "1991-01-01" @default.
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- W27492049 title "Noradrenaline-ATP corelease and cotransmission following activation of nicotine receptors at postganglionic sympathetic axons" @default.
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- W27492049 doi "https://doi.org/10.1007/978-3-7091-9175-0_12" @default.
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