FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2749329728> ?p ?o ?g. }

• W2749329728 endingPage "133" @default.
• W2749329728 startingPage "127" @default.
• W2749329728 abstract "Objective To evaluate population-based prostate cancer (CaP) testing of men in their 40s, given the paucity of prospective data evaluating the consequences of prostate-specific antigen (PSA) testing in younger men for CaP. Materials and Methods A total of 1052 men in their 40s were followed longitudinally for prostate outcomes, from 1990 to 2010. A random subset of 268 men was selected to undergo biennial CaP testing including PSA testing, transrectal ultrasound, and a digital rectal examination. A representative population of 609 men with a subset of 159 men who also began CaP testing in their 50s was also evaluated as a comparison group. Risk of prostate biopsy (PBx), CaP, or death from CaP was compared between CaP-tested and the routine-care population cohort. Results Median follow-up was 17.2 years. Men aged 40-49, who underwent CaP testing were 2.4 times more likely to undergo a PBx (hazard ratio [HR] 2.4 95% confidence interval [CI] 1.8-3.3) and 2.2 times more likely to be diagnosed with low-risk CaP (HR 2.2, 95% CI 1.12-4.0). Those initiating CaP testing a decade earlier were 2.2 times and 1.7 times more likely to be biopsied and be diagnosed with CaP for any given age (HR 2.2 95% CI 1.4-3.5 and 1.7 95% CI 1.1-2.7, respectively). Conclusion CaP testing in men beginning at age 40 resulted in a significant increase in the risk of PBx and diagnosis of low-risk CaP, without a measurable reduction in risk of CaP-death in this low-risk population. However, given the natural history of CaP, a longer follow-up is needed to confirm this finding. To evaluate population-based prostate cancer (CaP) testing of men in their 40s, given the paucity of prospective data evaluating the consequences of prostate-specific antigen (PSA) testing in younger men for CaP. A total of 1052 men in their 40s were followed longitudinally for prostate outcomes, from 1990 to 2010. A random subset of 268 men was selected to undergo biennial CaP testing including PSA testing, transrectal ultrasound, and a digital rectal examination. A representative population of 609 men with a subset of 159 men who also began CaP testing in their 50s was also evaluated as a comparison group. Risk of prostate biopsy (PBx), CaP, or death from CaP was compared between CaP-tested and the routine-care population cohort. Median follow-up was 17.2 years. Men aged 40-49, who underwent CaP testing were 2.4 times more likely to undergo a PBx (hazard ratio [HR] 2.4 95% confidence interval [CI] 1.8-3.3) and 2.2 times more likely to be diagnosed with low-risk CaP (HR 2.2, 95% CI 1.12-4.0). Those initiating CaP testing a decade earlier were 2.2 times and 1.7 times more likely to be biopsied and be diagnosed with CaP for any given age (HR 2.2 95% CI 1.4-3.5 and 1.7 95% CI 1.1-2.7, respectively). CaP testing in men beginning at age 40 resulted in a significant increase in the risk of PBx and diagnosis of low-risk CaP, without a measurable reduction in risk of CaP-death in this low-risk population. However, given the natural history of CaP, a longer follow-up is needed to confirm this finding." @default.
• W2749329728 created "2017-08-31" @default.
• W2749329728 creator A5001295981 @default.
• W2749329728 creator A5053084361 @default.
• W2749329728 creator A5067282152 @default.
• W2749329728 creator A5067816501 @default.
• W2749329728 creator A5091808340 @default.
• W2749329728 date "2017-12-01" @default.
• W2749329728 modified "2023-10-16" @default.
• W2749329728 title "The Effects of Population-based Prostate-specific Antigen Screening Beginning at Age 40" @default.
• W2749329728 cites W1976075687 @default.
• W2749329728 cites W1984455034 @default.
• W2749329728 cites W2042748219 @default.
• W2749329728 cites W2055968355 @default.
• W2749329728 cites W2075453908 @default.
• W2749329728 cites W2078065960 @default.
• W2749329728 cites W2080088297 @default.
• W2749329728 cites W2095761465 @default.
• W2749329728 cites W2106058419 @default.
• W2749329728 cites W2108391240 @default.
• W2749329728 cites W2110504486 @default.
• W2749329728 cites W2119692197 @default.
• W2749329728 cites W2134793522 @default.
• W2749329728 cites W2144298794 @default.
• W2749329728 cites W2145062298 @default.
• W2749329728 cites W2145221548 @default.
• W2749329728 cites W2150679001 @default.
• W2749329728 cites W2161311793 @default.
• W2749329728 cites W2235523093 @default.
• W2749329728 cites W2393681916 @default.
• W2749329728 cites W2461796878 @default.
• W2749329728 cites W2511949746 @default.
• W2749329728 cites W4252086282 @default.
• W2749329728 cites W4255100288 @default.
• W2749329728 cites W4295063935 @default.
• W2749329728 doi "https://doi.org/10.1016/j.urology.2017.08.012" @default.
• W2749329728 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5730083" @default.
• W2749329728 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28842211" @default.
• W2749329728 hasPublicationYear "2017" @default.
• W2749329728 type Work @default.
• W2749329728 sameAs 2749329728 @default.
• W2749329728 citedByCount "3" @default.
• W2749329728 countsByYear W27493297282018 @default.
• W2749329728 countsByYear W27493297282020 @default.
• W2749329728 crossrefType "journal-article" @default.
• W2749329728 hasAuthorship W2749329728A5001295981 @default.
• W2749329728 hasAuthorship W2749329728A5053084361 @default.
• W2749329728 hasAuthorship W2749329728A5067282152 @default.
• W2749329728 hasAuthorship W2749329728A5067816501 @default.
• W2749329728 hasAuthorship W2749329728A5091808340 @default.
• W2749329728 hasBestOaLocation W27493297282 @default.
• W2749329728 hasConcept C121608353 @default.
• W2749329728 hasConcept C126322002 @default.
• W2749329728 hasConcept C126894567 @default.
• W2749329728 hasConcept C188816634 @default.
• W2749329728 hasConcept C207103383 @default.
• W2749329728 hasConcept C2776235491 @default.
• W2749329728 hasConcept C2780101318 @default.
• W2749329728 hasConcept C2780192828 @default.
• W2749329728 hasConcept C2781217009 @default.
• W2749329728 hasConcept C2781406297 @default.
• W2749329728 hasConcept C2908647359 @default.
• W2749329728 hasConcept C29456083 @default.
• W2749329728 hasConcept C44249647 @default.
• W2749329728 hasConcept C71924100 @default.
• W2749329728 hasConcept C72563966 @default.
• W2749329728 hasConcept C99454951 @default.
• W2749329728 hasConceptScore W2749329728C121608353 @default.
• W2749329728 hasConceptScore W2749329728C126322002 @default.
• W2749329728 hasConceptScore W2749329728C126894567 @default.
• W2749329728 hasConceptScore W2749329728C188816634 @default.
• W2749329728 hasConceptScore W2749329728C207103383 @default.
• W2749329728 hasConceptScore W2749329728C2776235491 @default.
• W2749329728 hasConceptScore W2749329728C2780101318 @default.
• W2749329728 hasConceptScore W2749329728C2780192828 @default.
• W2749329728 hasConceptScore W2749329728C2781217009 @default.
• W2749329728 hasConceptScore W2749329728C2781406297 @default.
• W2749329728 hasConceptScore W2749329728C2908647359 @default.
• W2749329728 hasConceptScore W2749329728C29456083 @default.
• W2749329728 hasConceptScore W2749329728C44249647 @default.
• W2749329728 hasConceptScore W2749329728C71924100 @default.
• W2749329728 hasConceptScore W2749329728C72563966 @default.
• W2749329728 hasConceptScore W2749329728C99454951 @default.
• W2749329728 hasFunder F4320332161 @default.
• W2749329728 hasLocation W27493297281 @default.
• W2749329728 hasLocation W27493297282 @default.
• W2749329728 hasLocation W27493297283 @default.
• W2749329728 hasLocation W27493297284 @default.
• W2749329728 hasOpenAccess W2749329728 @default.
• W2749329728 hasPrimaryLocation W27493297281 @default.
• W2749329728 hasRelatedWork W1992657261 @default.
• W2749329728 hasRelatedWork W2049918799 @default.
• W2749329728 hasRelatedWork W2099948048 @default.
• W2749329728 hasRelatedWork W2143331076 @default.
• W2749329728 hasRelatedWork W2149157618 @default.
• W2749329728 hasRelatedWork W2897445903 @default.
• W2749329728 hasRelatedWork W2944341298 @default.
• W2749329728 hasRelatedWork W3129209394 @default.

• next