Matches in SemOpenAlex for { <https://semopenalex.org/work/W2749378346> ?p ?o ?g. }
- W2749378346 endingPage "260" @default.
- W2749378346 startingPage "260" @default.
- W2749378346 abstract "Abstract: A new cyclopentenone, 5-hydroxycyclopeni cillone (1), was isolated together with three known compounds, ar-turmerone (2), citreoisocoumarin (3), and 6-O-methyl-citreoisocoumarin (4), from a culture of the sponge-derived fungus Trichoderma sp. HPQJ-34. The structures of 1-4 were characterized using comprehensive spectroscopic analyses. The absolute configuration of 1 was determined by comparison of electronic circular dichroism (ECD) spectra with literature values used for the reported analogue, cyclopenicillone (5), which was not isolated in this research. Compound 1 was shown to scavenge 2,2-diphenyl-1-picrylhydrazyl free radicals, and decrease β-amyloid (Aβ) fibrillization in vitro. Moreover, 1 significantly reduced H₂O₂-induced neurotoxicity in SH-SY5Y cells. These findings suggested that compound 1, a newly discovered cyclopentenone, has moderate anti-oxidative, anti-Aβ fibrillization properties and neuroprotective effects, and might be a good free radical scavenger." @default.
- W2749378346 created "2017-08-31" @default.
- W2749378346 creator A5001736408 @default.
- W2749378346 creator A5012178764 @default.
- W2749378346 creator A5012429750 @default.
- W2749378346 creator A5029385936 @default.
- W2749378346 creator A5043490198 @default.
- W2749378346 creator A5049804114 @default.
- W2749378346 creator A5054125069 @default.
- W2749378346 creator A5054718134 @default.
- W2749378346 creator A5057614857 @default.
- W2749378346 creator A5068348283 @default.
- W2749378346 creator A5071599697 @default.
- W2749378346 creator A5071666503 @default.
- W2749378346 creator A5078651116 @default.
- W2749378346 creator A5080095549 @default.
- W2749378346 date "2017-08-19" @default.
- W2749378346 modified "2023-10-06" @default.
- W2749378346 title "5-Hydroxycyclopenicillone, a New β-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp. HPQJ-34" @default.
- W2749378346 cites W1554868992 @default.
- W2749378346 cites W1578829945 @default.
- W2749378346 cites W1814086198 @default.
- W2749378346 cites W1860832468 @default.
- W2749378346 cites W1975758354 @default.
- W2749378346 cites W1975769729 @default.
- W2749378346 cites W1976495393 @default.
- W2749378346 cites W1994767260 @default.
- W2749378346 cites W2014652462 @default.
- W2749378346 cites W2030524229 @default.
- W2749378346 cites W2032092910 @default.
- W2749378346 cites W2032553134 @default.
- W2749378346 cites W2035158433 @default.
- W2749378346 cites W2035795387 @default.
- W2749378346 cites W2038332195 @default.
- W2749378346 cites W2039069312 @default.
- W2749378346 cites W2043289059 @default.
- W2749378346 cites W2053691649 @default.
- W2749378346 cites W2060992279 @default.
- W2749378346 cites W2111077672 @default.
- W2749378346 cites W2147371111 @default.
- W2749378346 cites W2148482851 @default.
- W2749378346 cites W2178968939 @default.
- W2749378346 cites W2185348657 @default.
- W2749378346 cites W2282563036 @default.
- W2749378346 cites W2324491595 @default.
- W2749378346 cites W2393359533 @default.
- W2749378346 cites W2534292362 @default.
- W2749378346 cites W2547982875 @default.
- W2749378346 cites W394052542 @default.
- W2749378346 cites W4211213171 @default.
- W2749378346 cites W4251247786 @default.
- W2749378346 cites W4256176203 @default.
- W2749378346 doi "https://doi.org/10.3390/md15080260" @default.
- W2749378346 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5577614" @default.
- W2749378346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28825620" @default.
- W2749378346 hasPublicationYear "2017" @default.
- W2749378346 type Work @default.
- W2749378346 sameAs 2749378346 @default.
- W2749378346 citedByCount "24" @default.
- W2749378346 countsByYear W27493783462017 @default.
- W2749378346 countsByYear W27493783462018 @default.
- W2749378346 countsByYear W27493783462019 @default.
- W2749378346 countsByYear W27493783462020 @default.
- W2749378346 countsByYear W27493783462021 @default.
- W2749378346 countsByYear W27493783462022 @default.
- W2749378346 countsByYear W27493783462023 @default.
- W2749378346 crossrefType "journal-article" @default.
- W2749378346 hasAuthorship W2749378346A5001736408 @default.
- W2749378346 hasAuthorship W2749378346A5012178764 @default.
- W2749378346 hasAuthorship W2749378346A5012429750 @default.
- W2749378346 hasAuthorship W2749378346A5029385936 @default.
- W2749378346 hasAuthorship W2749378346A5043490198 @default.
- W2749378346 hasAuthorship W2749378346A5049804114 @default.
- W2749378346 hasAuthorship W2749378346A5054125069 @default.
- W2749378346 hasAuthorship W2749378346A5054718134 @default.
- W2749378346 hasAuthorship W2749378346A5057614857 @default.
- W2749378346 hasAuthorship W2749378346A5068348283 @default.
- W2749378346 hasAuthorship W2749378346A5071599697 @default.
- W2749378346 hasAuthorship W2749378346A5071666503 @default.
- W2749378346 hasAuthorship W2749378346A5078651116 @default.
- W2749378346 hasAuthorship W2749378346A5080095549 @default.
- W2749378346 hasBestOaLocation W27493783461 @default.
- W2749378346 hasConcept C133571119 @default.
- W2749378346 hasConcept C139066938 @default.
- W2749378346 hasConcept C178790620 @default.
- W2749378346 hasConcept C179104552 @default.
- W2749378346 hasConcept C181199279 @default.
- W2749378346 hasConcept C185592680 @default.
- W2749378346 hasConcept C202751555 @default.
- W2749378346 hasConcept C2776151105 @default.
- W2749378346 hasConcept C2777633098 @default.
- W2749378346 hasConcept C2777903533 @default.
- W2749378346 hasConcept C2779491297 @default.
- W2749378346 hasConcept C2779678110 @default.
- W2749378346 hasConcept C2780857362 @default.
- W2749378346 hasConcept C29730261 @default.
- W2749378346 hasConcept C2992339995 @default.
- W2749378346 hasConcept C55493867 @default.