Matches in SemOpenAlex for { <https://semopenalex.org/work/W2749496257> ?p ?o ?g. }
- W2749496257 abstract "North America is currently in the grips of a crisis rooted in the use of licit and illicit opioid-based analgesics. Drug overdose is the leading cause of accidental death in Canada and the US, and the growing toll of opioid-related morbidity and mortality requires a diversity of novel therapeutic and harm reduction-based interventions. Research suggests that increasing adult access to both medical and recreational cannabis has significant positive impacts on public health and safety as a result of substitution effect. Observational and epidemiological studies have found that medical cannabis programs are associated with a reduction in the use of opioids and associated morbidity and mortality. This paper presents an evidence-based rationale for cannabis-based interventions in the opioid overdose crisis informed by research on substitution effect, proposing three important windows of opportunity for cannabis for therapeutic purposes (CTP) to play a role in reducing opioid use and interrupting the cycle towards opioid use disorder: 1) prior to opioid introduction in the treatment of chronic pain; 2) as an opioid reduction strategy for those patients already using opioids; and 3) as an adjunct therapy to methadone or suboxone treatment in order to increase treatment success rates. The commentary explores potential obstacles and limitations to these proposed interventions, and as well as strategies to monitor their impact on public health and safety. The growing body of research supporting the medical use of cannabis as an adjunct or substitute for opioids creates an evidence-based rationale for governments, health care providers, and academic researchers to consider the implementation and assessment of cannabis-based interventions in the opioid crisis." @default.
- W2749496257 created "2017-08-31" @default.
- W2749496257 creator A5035932793 @default.
- W2749496257 date "2017-08-18" @default.
- W2749496257 modified "2023-10-17" @default.
- W2749496257 title "Rationale for cannabis-based interventions in the opioid overdose crisis" @default.
- W2749496257 cites W1235781926 @default.
- W2749496257 cites W1574358946 @default.
- W2749496257 cites W1639811251 @default.
- W2749496257 cites W1907921830 @default.
- W2749496257 cites W1929097547 @default.
- W2749496257 cites W1965005771 @default.
- W2749496257 cites W1980063428 @default.
- W2749496257 cites W1996672820 @default.
- W2749496257 cites W2001768125 @default.
- W2749496257 cites W2002079546 @default.
- W2749496257 cites W2028822574 @default.
- W2749496257 cites W2040320300 @default.
- W2749496257 cites W2043579293 @default.
- W2749496257 cites W2085610044 @default.
- W2749496257 cites W2091054811 @default.
- W2749496257 cites W2094379442 @default.
- W2749496257 cites W2101705297 @default.
- W2749496257 cites W2108766309 @default.
- W2749496257 cites W2109773598 @default.
- W2749496257 cites W2109927649 @default.
- W2749496257 cites W2119867825 @default.
- W2749496257 cites W2120142285 @default.
- W2749496257 cites W2123439904 @default.
- W2749496257 cites W2127438675 @default.
- W2749496257 cites W2145087250 @default.
- W2749496257 cites W2149240364 @default.
- W2749496257 cites W2151383246 @default.
- W2749496257 cites W2160313238 @default.
- W2749496257 cites W2160421955 @default.
- W2749496257 cites W2164672098 @default.
- W2749496257 cites W2183867796 @default.
- W2749496257 cites W2343082716 @default.
- W2749496257 cites W2468692760 @default.
- W2749496257 cites W2493299638 @default.
- W2749496257 cites W2514903360 @default.
- W2749496257 cites W2530925494 @default.
- W2749496257 cites W2561135550 @default.
- W2749496257 cites W2564868454 @default.
- W2749496257 cites W2586995002 @default.
- W2749496257 cites W2611784412 @default.
- W2749496257 cites W2693016255 @default.
- W2749496257 cites W2729672332 @default.
- W2749496257 doi "https://doi.org/10.1186/s12954-017-0183-9" @default.
- W2749496257 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5563007" @default.
- W2749496257 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28821296" @default.
- W2749496257 hasPublicationYear "2017" @default.
- W2749496257 type Work @default.
- W2749496257 sameAs 2749496257 @default.
- W2749496257 citedByCount "68" @default.
- W2749496257 countsByYear W27494962572018 @default.
- W2749496257 countsByYear W27494962572019 @default.
- W2749496257 countsByYear W27494962572020 @default.
- W2749496257 countsByYear W27494962572021 @default.
- W2749496257 countsByYear W27494962572022 @default.
- W2749496257 countsByYear W27494962572023 @default.
- W2749496257 crossrefType "journal-article" @default.
- W2749496257 hasAuthorship W2749496257A5035932793 @default.
- W2749496257 hasBestOaLocation W27494962571 @default.
- W2749496257 hasConcept C118552586 @default.
- W2749496257 hasConcept C126322002 @default.
- W2749496257 hasConcept C138816342 @default.
- W2749496257 hasConcept C155164915 @default.
- W2749496257 hasConcept C159110408 @default.
- W2749496257 hasConcept C170493617 @default.
- W2749496257 hasConcept C177713679 @default.
- W2749496257 hasConcept C27415008 @default.
- W2749496257 hasConcept C2777056318 @default.
- W2749496257 hasConcept C2778750930 @default.
- W2749496257 hasConcept C2778767360 @default.
- W2749496257 hasConcept C2779148768 @default.
- W2749496257 hasConcept C2779418921 @default.
- W2749496257 hasConcept C2781063702 @default.
- W2749496257 hasConcept C529928208 @default.
- W2749496257 hasConcept C71924100 @default.
- W2749496257 hasConceptScore W2749496257C118552586 @default.
- W2749496257 hasConceptScore W2749496257C126322002 @default.
- W2749496257 hasConceptScore W2749496257C138816342 @default.
- W2749496257 hasConceptScore W2749496257C155164915 @default.
- W2749496257 hasConceptScore W2749496257C159110408 @default.
- W2749496257 hasConceptScore W2749496257C170493617 @default.
- W2749496257 hasConceptScore W2749496257C177713679 @default.
- W2749496257 hasConceptScore W2749496257C27415008 @default.
- W2749496257 hasConceptScore W2749496257C2777056318 @default.
- W2749496257 hasConceptScore W2749496257C2778750930 @default.
- W2749496257 hasConceptScore W2749496257C2778767360 @default.
- W2749496257 hasConceptScore W2749496257C2779148768 @default.
- W2749496257 hasConceptScore W2749496257C2779418921 @default.
- W2749496257 hasConceptScore W2749496257C2781063702 @default.
- W2749496257 hasConceptScore W2749496257C529928208 @default.
- W2749496257 hasConceptScore W2749496257C71924100 @default.
- W2749496257 hasIssue "1" @default.
- W2749496257 hasLocation W27494962571 @default.
- W2749496257 hasLocation W27494962572 @default.
- W2749496257 hasLocation W27494962573 @default.