FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2749561277> ?p ?o ?g. }

• W2749561277 endingPage "101" @default.
• W2749561277 startingPage "87" @default.
• W2749561277 abstract "A coupled agent-based model (ABM) and finite element analysis (FEA) computational framework is developed to study the interplay of bio-chemo-mechanical factors in blood vessels and their role in maintaining homeostasis. The agent-based model implements the power of REPAST Simphony libraries and adapts its environment for biological simulations. Coupling a continuum-level model (FEA) to a cellular-level model (ABM) has enabled this computational framework to capture the response of blood vessels to increased or decreased levels of growth factors, proteases and other signaling molecules (on the micro scale) as well as altered blood pressure. Performance of the model is assessed by simulating porcine left anterior descending artery under normotensive conditions and transient increases in blood pressure and by analyzing sensitivity of the model to variations in the rule parameters of the ABM. These simulations proved that the model is stable under normotensive conditions and can recover from transient increases in blood pressure. Sensitivity studies revealed that the model is most sensitive to variations in the concentration of growth factors that affect cellular proliferation and regulate extracellular matrix composition (mainly collagen)." @default.
• W2749561277 created "2017-08-31" @default.
• W2749561277 creator A5020703953 @default.
• W2749561277 creator A5031038097 @default.
• W2749561277 creator A5060769251 @default.
• W2749561277 date "2017-08-19" @default.
• W2749561277 modified "2023-10-18" @default.
• W2749561277 title "Mechanobiological model of arterial growth and remodeling" @default.
• W2749561277 cites W1488444587 @default.
• W2749561277 cites W1490293848 @default.
• W2749561277 cites W1921434079 @default.
• W2749561277 cites W1945199177 @default.
• W2749561277 cites W1964195356 @default.
• W2749561277 cites W1965366994 @default.
• W2749561277 cites W1968657221 @default.
• W2749561277 cites W1968913969 @default.
• W2749561277 cites W1975003286 @default.
• W2749561277 cites W1979530095 @default.
• W2749561277 cites W1981125440 @default.
• W2749561277 cites W1984385506 @default.
• W2749561277 cites W1987150966 @default.
• W2749561277 cites W1988059443 @default.
• W2749561277 cites W1999342475 @default.
• W2749561277 cites W2003617951 @default.
• W2749561277 cites W2005778784 @default.
• W2749561277 cites W2006550454 @default.
• W2749561277 cites W2011667258 @default.
• W2749561277 cites W2014575233 @default.
• W2749561277 cites W2017327254 @default.
• W2749561277 cites W2018941696 @default.
• W2749561277 cites W2019132257 @default.
• W2749561277 cites W2020373346 @default.
• W2749561277 cites W2024771744 @default.
• W2749561277 cites W2034109005 @default.
• W2749561277 cites W2035469813 @default.
• W2749561277 cites W2041820816 @default.
• W2749561277 cites W2041990686 @default.
• W2749561277 cites W2043797885 @default.
• W2749561277 cites W2047161807 @default.
• W2749561277 cites W2048117807 @default.
• W2749561277 cites W2048333870 @default.
• W2749561277 cites W2048783182 @default.
• W2749561277 cites W2049454597 @default.
• W2749561277 cites W2051643627 @default.
• W2749561277 cites W2056458634 @default.
• W2749561277 cites W2058802253 @default.
• W2749561277 cites W2063275122 @default.
• W2749561277 cites W2064196833 @default.
• W2749561277 cites W2068156242 @default.
• W2749561277 cites W2070199635 @default.
• W2749561277 cites W2076266519 @default.
• W2749561277 cites W2076590436 @default.
• W2749561277 cites W2082523022 @default.
• W2749561277 cites W2083912668 @default.
• W2749561277 cites W2085641706 @default.
• W2749561277 cites W2089325024 @default.
• W2749561277 cites W2089635064 @default.
• W2749561277 cites W2092663627 @default.
• W2749561277 cites W2096195817 @default.
• W2749561277 cites W2097792029 @default.
• W2749561277 cites W2100185884 @default.
• W2749561277 cites W2103227883 @default.
• W2749561277 cites W2104976364 @default.
• W2749561277 cites W2109109177 @default.
• W2749561277 cites W2109995938 @default.
• W2749561277 cites W2110937552 @default.
• W2749561277 cites W2117305455 @default.
• W2749561277 cites W2119346746 @default.
• W2749561277 cites W2122931571 @default.
• W2749561277 cites W2124563099 @default.
• W2749561277 cites W2126284874 @default.
• W2749561277 cites W2128512270 @default.
• W2749561277 cites W2134797319 @default.
• W2749561277 cites W2135531568 @default.
• W2749561277 cites W2141115146 @default.
• W2749561277 cites W2142311054 @default.
• W2749561277 cites W2143843964 @default.
• W2749561277 cites W2145677179 @default.
• W2749561277 cites W2153373747 @default.
• W2749561277 cites W2156171664 @default.
• W2749561277 cites W2161160262 @default.
• W2749561277 cites W2165089503 @default.
• W2749561277 cites W2167243609 @default.
• W2749561277 cites W2183737922 @default.
• W2749561277 cites W2399805922 @default.
• W2749561277 cites W2414963831 @default.
• W2749561277 cites W2476542314 @default.
• W2749561277 cites W2480924511 @default.
• W2749561277 cites W2524610039 @default.
• W2749561277 cites W71942302 @default.
• W2749561277 doi "https://doi.org/10.1007/s10237-017-0946-y" @default.
• W2749561277 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6292683" @default.
• W2749561277 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28823079" @default.
• W2749561277 hasPublicationYear "2017" @default.
• W2749561277 type Work @default.
• W2749561277 sameAs 2749561277 @default.
• W2749561277 citedByCount "25" @default.
• W2749561277 countsByYear W27495612772018 @default.

• next