FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2749972521> ?p ?o ?g. }

• W2749972521 abstract "The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced to prevent invasive pneumococcal disease (IPD) in Western Australian (WA) Aboriginal people in 2001. PCV13 replaced PCV7 in July 2011, covering six additional pneumococcal serotypes; however, IPD rates remained high in Aboriginal people in WA. Upper respiratory tract pneumococcal carriage can precede IPD, and PCVs alter serotype distribution. To assess the impact of PCV13 introduction, identify emerging serotypes, and assess risk factors for carriage, nasopharyngeal swabs and information on demographic characteristics, health, medication and living conditions from Aboriginal children and adults across WA from August 2008 to November 2014 were collected. Bacteria were cultured using selective media and pneumococcal isolates were serotyped by Quellung reaction. Risk factors were analysed by multivariable logistic regression. One thousand five hundred swabs pre- and 1385 swabs post-PCV13 introduction were collected. Pneumococcal carriage was detected in 66.8% of children <5 years old and 53.2% of 5–14 year-olds post-PCV13, compared with pre-PCV13 prevalence of 72.2% and 49.4%, respectively. The prevalence of PCV13-non-PCV7 serotypes decreased in children <5 years old from 13.5% pre-PCV13 to 5.8% post-PCV13 (p < 0.01), and from 8.4% to 6.1% in children 5–14 years old (p > 0.05). The most common serotypes post-PCV13 were 11A (prevalence 4.0%), 15B (3.5%), 16F (3.5%), and 19F (3.2%). Risk of detection of pneumococcal carriage increased until age 12 months (odds ratio [OR] 4.19, 95% confidence interval [CI] 2.39–7.33), with nasal discharge (OR 2.49 [95% CI 2.00–3.09]), residence in a remote community (OR 2.21 [95% CI 1.67–2.92]) and household crowding (OR 1.36 [95% CI 1.11–1.67]). Recent antibiotic use was negatively associated with pneumococcal carriage (OR 0.48 [95% CI 0.33–0.69]). Complete resistance to penicillin was present among isolates of serotypes 19A (6.0%), 19F (2.3%) and non-serotypeable isolates (1.9%). Serotype 23F and newly emerged serotype 7B isolates showed high rates of resistance to cotrimoxazole, erythromycin and tetracycline (86.9%, 86.9%, 82.0%, respectively for 23F, 100.0%, 100.0% and 93.3% for 7B). Since PCV13 replaced PCV7, carriage of PCV13-non-PCV7 serotypes decreased significantly among children <5 years old, those most likely to have received PCV13, and to a lesser extent in older people. Known risk factors for carriage including crowding and young age remain in the Aboriginal population." @default.
• W2749972521 created "2017-08-31" @default.
• W2749972521 creator A5002975177 @default.
• W2749972521 creator A5012521967 @default.
• W2749972521 creator A5038189604 @default.
• W2749972521 creator A5041233703 @default.
• W2749972521 creator A5061884440 @default.
• W2749972521 creator A5065678436 @default.
• W2749972521 creator A5087063535 @default.
• W2749972521 creator A5091845635 @default.
• W2749972521 date "2017-09-25" @default.
• W2749972521 modified "2023-09-27" @default.
• W2749972521 title "Predictors of pneumococcal carriage and the effect of the 13-valent pneumococcal conjugate vaccination in the Western Australian Aboriginal population" @default.
• W2749972521 cites W133071462 @default.
• W2749972521 cites W1974413001 @default.
• W2749972521 cites W1977910742 @default.
• W2749972521 cites W1978695182 @default.
• W2749972521 cites W1998572742 @default.
• W2749972521 cites W1998732075 @default.
• W2749972521 cites W2012956053 @default.
• W2749972521 cites W2057443006 @default.
• W2749972521 cites W2063701791 @default.
• W2749972521 cites W2064694000 @default.
• W2749972521 cites W2082036615 @default.
• W2749972521 cites W2095698808 @default.
• W2749972521 cites W2097188627 @default.
• W2749972521 cites W2121532020 @default.
• W2749972521 cites W2146981090 @default.
• W2749972521 cites W2156404536 @default.
• W2749972521 cites W2201080315 @default.
• W2749972521 cites W2268506593 @default.
• W2749972521 cites W2301114847 @default.
• W2749972521 cites W2358425299 @default.
• W2749972521 cites W2510565718 @default.
• W2749972521 cites W2534695322 @default.
• W2749972521 cites W2915476661 @default.
• W2749972521 cites W2228014882 @default.
• W2749972521 doi "https://doi.org/10.1186/s41479-017-0038-x" @default.
• W2749972521 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5611608" @default.
• W2749972521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29021946" @default.
• W2749972521 hasPublicationYear "2017" @default.
• W2749972521 type Work @default.
• W2749972521 sameAs 2749972521 @default.
• W2749972521 citedByCount "21" @default.
• W2749972521 countsByYear W27499725212018 @default.
• W2749972521 countsByYear W27499725212019 @default.
• W2749972521 countsByYear W27499725212020 @default.
• W2749972521 countsByYear W27499725212021 @default.
• W2749972521 countsByYear W27499725212022 @default.
• W2749972521 crossrefType "journal-article" @default.
• W2749972521 hasAuthorship W2749972521A5002975177 @default.
• W2749972521 hasAuthorship W2749972521A5012521967 @default.
• W2749972521 hasAuthorship W2749972521A5038189604 @default.
• W2749972521 hasAuthorship W2749972521A5041233703 @default.
• W2749972521 hasAuthorship W2749972521A5061884440 @default.
• W2749972521 hasAuthorship W2749972521A5065678436 @default.
• W2749972521 hasAuthorship W2749972521A5087063535 @default.
• W2749972521 hasAuthorship W2749972521A5091845635 @default.
• W2749972521 hasBestOaLocation W27499725211 @default.
• W2749972521 hasConcept C10389963 @default.
• W2749972521 hasConcept C126322002 @default.
• W2749972521 hasConcept C142724271 @default.
• W2749972521 hasConcept C156957248 @default.
• W2749972521 hasConcept C187212893 @default.
• W2749972521 hasConcept C203014093 @default.
• W2749972521 hasConcept C22070199 @default.
• W2749972521 hasConcept C2778866548 @default.
• W2749972521 hasConcept C2781253189 @default.
• W2749972521 hasConcept C2908647359 @default.
• W2749972521 hasConcept C32762888 @default.
• W2749972521 hasConcept C44249647 @default.
• W2749972521 hasConcept C501593827 @default.
• W2749972521 hasConcept C71924100 @default.
• W2749972521 hasConcept C86803240 @default.
• W2749972521 hasConcept C89423630 @default.
• W2749972521 hasConcept C99454951 @default.
• W2749972521 hasConceptScore W2749972521C10389963 @default.
• W2749972521 hasConceptScore W2749972521C126322002 @default.
• W2749972521 hasConceptScore W2749972521C142724271 @default.
• W2749972521 hasConceptScore W2749972521C156957248 @default.
• W2749972521 hasConceptScore W2749972521C187212893 @default.
• W2749972521 hasConceptScore W2749972521C203014093 @default.
• W2749972521 hasConceptScore W2749972521C22070199 @default.
• W2749972521 hasConceptScore W2749972521C2778866548 @default.
• W2749972521 hasConceptScore W2749972521C2781253189 @default.
• W2749972521 hasConceptScore W2749972521C2908647359 @default.
• W2749972521 hasConceptScore W2749972521C32762888 @default.
• W2749972521 hasConceptScore W2749972521C44249647 @default.
• W2749972521 hasConceptScore W2749972521C501593827 @default.
• W2749972521 hasConceptScore W2749972521C71924100 @default.
• W2749972521 hasConceptScore W2749972521C86803240 @default.
• W2749972521 hasConceptScore W2749972521C89423630 @default.
• W2749972521 hasConceptScore W2749972521C99454951 @default.
• W2749972521 hasFunder F4320323612 @default.
• W2749972521 hasFunder F4320334705 @default.
• W2749972521 hasIssue "1" @default.
• W2749972521 hasLocation W27499725211 @default.
• W2749972521 hasLocation W27499725212 @default.
• W2749972521 hasLocation W27499725213 @default.
• W2749972521 hasLocation W27499725214 @default.

• next