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- W2749986715 endingPage "79" @default.
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- W2749986715 abstract "With the growing usage of nanoparticles (NPs) in industry, biomedicine, and daily life, an increasing chance for humans to be exposed to NPs has been issued. However, the basis of toxicity of most manufactured NPs is not fully understood. An important mechanism of nanotoxicity is reactive oxygen species (ROS) formation, which could cause oxidative stress, inflammation, and consequent cell death. NPs can interact with H2O or O2 in the physiological environment, resulting in the direct production of ROS, or affect the function of mitochondria and NADPH oxidase, resulting in the indirect production of ROS. ROS generation and oxidative stress were depicted by the hierarchical oxidative stress model. Critical determinants that can affect the generation of ROS, including NPs’ composition, size, shape, and surface chemistry, are briefly discussed in this review." @default.
- W2749986715 created "2017-08-31" @default.
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- W2749986715 creator A5071428990 @default.
- W2749986715 creator A5087198508 @default.
- W2749986715 date "2017-01-01" @default.
- W2749986715 modified "2023-09-28" @default.
- W2749986715 title "Nanoparticles-Induced Oxidative Stress" @default.
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- W2749986715 doi "https://doi.org/10.1007/978-981-10-5864-6_4" @default.
- W2749986715 hasPublicationYear "2017" @default.
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