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- W2750055405 abstract "In a sample of 442 births from the Child Health and Development Studies cohort, we examined associations between maternal prenatal exposure to hydroxylated polychlorinated biphenyl metabolites (OH-PCBs) and pregnancy outcomes, and whether associations were mediated by maternal thyroid hormone levels and/or modified by maternal smoking. Compared to nonsmokers, smokers had twice the mean concentration of 4-OH-CB107 (p < 0.001) and lower levels of its parent compound, PCB118 (p = 0.001). Among mothers who smoked, the birth weight of newborns with maternal concentrations of 4-OH-CB107 in the upper quartile was 316 g lighter (95% confidence interval (CI) 566, 65) compared to those with maternal concentrations in the lowest quartile, after control for PCB118 and other potential confounders. This association was not observed for non-smoking mothers and was not mediated by maternal thyroid hormone levels. Maternal prenatal 4-OH-CB107 levels appear to be influenced by maternal smoking and contribute to lower birth weight among smokers." @default.
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- W2750055405 date "2017-09-01" @default.
- W2750055405 modified "2023-09-26" @default.
- W2750055405 title "Functional foods in gestational diabetes: Evaluation of the oral glucose tolerance test (OGTT) in pregnant rats treated with mushrooms" @default.
- W2750055405 doi "https://doi.org/10.1016/j.reprotox.2017.06.151" @default.
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