Matches in SemOpenAlex for { <https://semopenalex.org/work/W2750065579> ?p ?o ?g. }
- W2750065579 abstract "The dark sleeper (Odontobutis potamophila) is an important commercial fish species which shows a sexually dimorphic growth pattern. However, the lack of sex transcriptomic data is hindering further research and genetically selective breeding of the dark sleeper. In this study, integrated analysis of mRNA and miRNA was performed on gonad tissue to elucidate the molecular mechanisms of sex determination and differentiation in the dark sleeper.A total of 143 differentially expressed miRNAs and 16,540 differentially expressed genes were identified. Of these, 8103 mRNAs and 75 miRNAs were upregulated in testes, and 8437 mRNAs and 68 miRNAs were upregulated in ovaries. Integrated analysis of miRNA and mRNA expression profiles predicted more than 50,000 miRNA-mRNA interaction sites, and among them 27,583 negative miRNA-mRNA interactions. A number of sex related genes were targeted by sex-biased miRNAs. The relationship between 15 sex-biased genes and 15 sex-biased miRNAs verified by using qRT-PCR were described. Additionally, a number of SNPs were revealed through the transcriptome data.The overall results of this study facilitate our understanding of the molecular mechanism underlying sex determination and differentiation and provide valuable genomic information for selective breeding of the dark sleeper." @default.
- W2750065579 created "2017-08-31" @default.
- W2750065579 creator A5032415636 @default.
- W2750065579 creator A5039708796 @default.
- W2750065579 creator A5041365684 @default.
- W2750065579 creator A5049295979 @default.
- W2750065579 creator A5058771046 @default.
- W2750065579 creator A5068831513 @default.
- W2750065579 creator A5083211713 @default.
- W2750065579 date "2017-08-14" @default.
- W2750065579 modified "2023-10-14" @default.
- W2750065579 title "Integrated analysis of mRNA-seq and miRNA-seq reveals the potential roles of sex-biased miRNA-mRNA pairs in gonad tissue of dark sleeper (Odontobutis potamophila)" @default.
- W2750065579 cites W127566521 @default.
- W2750065579 cites W144423133 @default.
- W2750065579 cites W1731637226 @default.
- W2750065579 cites W1841658720 @default.
- W2750065579 cites W1865976688 @default.
- W2750065579 cites W1908886342 @default.
- W2750065579 cites W1912104500 @default.
- W2750065579 cites W195900143 @default.
- W2750065579 cites W1967155546 @default.
- W2750065579 cites W1971546287 @default.
- W2750065579 cites W1985207433 @default.
- W2750065579 cites W1988907214 @default.
- W2750065579 cites W1990092024 @default.
- W2750065579 cites W1995816084 @default.
- W2750065579 cites W1996630410 @default.
- W2750065579 cites W1999434762 @default.
- W2750065579 cites W2000113246 @default.
- W2750065579 cites W2003448091 @default.
- W2750065579 cites W2007776002 @default.
- W2750065579 cites W2008268323 @default.
- W2750065579 cites W2009550994 @default.
- W2750065579 cites W2011463435 @default.
- W2750065579 cites W2012590291 @default.
- W2750065579 cites W2015750766 @default.
- W2750065579 cites W2018813669 @default.
- W2750065579 cites W2019018720 @default.
- W2750065579 cites W2022822215 @default.
- W2750065579 cites W2026248557 @default.
- W2750065579 cites W2026706442 @default.
- W2750065579 cites W2027411393 @default.
- W2750065579 cites W2030937967 @default.
- W2750065579 cites W2032281322 @default.
- W2750065579 cites W2032571761 @default.
- W2750065579 cites W2036760181 @default.
- W2750065579 cites W2038518561 @default.
- W2750065579 cites W2038707074 @default.
- W2750065579 cites W2041668798 @default.
- W2750065579 cites W2044122626 @default.
- W2750065579 cites W2044932541 @default.
- W2750065579 cites W2049503648 @default.
- W2750065579 cites W2052531669 @default.
- W2750065579 cites W2056201218 @default.
- W2750065579 cites W2061734201 @default.
- W2750065579 cites W2064292256 @default.
- W2750065579 cites W2065422721 @default.
- W2750065579 cites W2070053574 @default.
- W2750065579 cites W2072944743 @default.
- W2750065579 cites W2074872010 @default.
- W2750065579 cites W2075458954 @default.
- W2750065579 cites W2085140131 @default.
- W2750065579 cites W2085588348 @default.
- W2750065579 cites W2086721579 @default.
- W2750065579 cites W2088797440 @default.
- W2750065579 cites W2089798340 @default.
- W2750065579 cites W2095229198 @default.
- W2750065579 cites W2099048062 @default.
- W2750065579 cites W2102190537 @default.
- W2750065579 cites W2112785261 @default.
- W2750065579 cites W2113584562 @default.
- W2750065579 cites W2115206563 @default.
- W2750065579 cites W2117148848 @default.
- W2750065579 cites W2117840333 @default.
- W2750065579 cites W2121166984 @default.
- W2750065579 cites W2126814743 @default.
- W2750065579 cites W2142515731 @default.
- W2750065579 cites W2142839629 @default.
- W2750065579 cites W2151534369 @default.
- W2750065579 cites W2158701974 @default.
- W2750065579 cites W2162674813 @default.
- W2750065579 cites W2164750690 @default.
- W2750065579 cites W2167072163 @default.
- W2750065579 cites W2167540560 @default.
- W2750065579 cites W2175842617 @default.
- W2750065579 cites W2282819757 @default.
- W2750065579 cites W2291352087 @default.
- W2750065579 cites W2326119666 @default.
- W2750065579 cites W2330778891 @default.
- W2750065579 cites W2335224273 @default.
- W2750065579 cites W2410796442 @default.
- W2750065579 cites W4230020082 @default.
- W2750065579 doi "https://doi.org/10.1186/s12864-017-3995-9" @default.
- W2750065579 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5557427" @default.
- W2750065579 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28806919" @default.
- W2750065579 hasPublicationYear "2017" @default.
- W2750065579 type Work @default.
- W2750065579 sameAs 2750065579 @default.
- W2750065579 citedByCount "29" @default.
- W2750065579 countsByYear W27500655792018 @default.