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• W2750536031 startingPage "e000218" @default.
• W2750536031 abstract "The large bowel shows biomolecular, anatomical and bacterial changes that proceed from the proximal to the distal tract. These changes account for the different behaviour of colon cancers arising from the diverse sides of the colon–rectum as well as for the sensitivity to the therapy, including immunotherapy. The gut microbiota plays an important role in the modulation of the immune response and differs between the right colon cancer and the left colorectal cancer. The qualitative and quantitative difference of the commensal bacteria between the right side and the left side induces epigenetic changes in the intestinal epithelial cells as well as in the resident immune population. The second player in the pathological homeostasis of colorectal cancer is the differences of the genetic features of cancer cells and the different effects that microsatellite instability, chromosomal instability and the CpG island methylator phenotype induce on the immunological organisation of the tumour microenvironment. The third player is the immunological composition of the tumour microenvironment, which changes under the influence of both genetic structures and gut microbiota. All these three players influence each other. This review describes these three aspects, highlights their interactions and discusses data from reported clinical trials.Podcast audio/cms/asset/58445f0d-e903-4073-b505-ebf134af8cad/mmc1.mp3Loading ... Download .mp3 (24.75 MB) Help with .mp3 files" @default.
• W2750536031 created "2017-08-31" @default.
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• W2750536031 date "2017-01-01" @default.
• W2750536031 modified "2023-10-16" @default.
• W2750536031 title "Heterogeneity of colon cancer: from bench to bedside" @default.
• W2750536031 cites W1498931318 @default.
• W2750536031 cites W1500247462 @default.
• W2750536031 cites W1565911218 @default.
• W2750536031 cites W1576543020 @default.
• W2750536031 cites W1603230122 @default.
• W2750536031 cites W1785380284 @default.
• W2750536031 cites W1856892620 @default.
• W2750536031 cites W1880594232 @default.
• W2750536031 cites W1940241680 @default.
• W2750536031 cites W1981253630 @default.
• W2750536031 cites W1983428284 @default.
• W2750536031 cites W1990236675 @default.
• W2750536031 cites W1991804457 @default.
• W2750536031 cites W1999498760 @default.
• W2750536031 cites W2003593390 @default.
• W2750536031 cites W2015649564 @default.
• W2750536031 cites W2030797581 @default.
• W2750536031 cites W2037900813 @default.
• W2750536031 cites W2039123767 @default.
• W2750536031 cites W2039247111 @default.
• W2750536031 cites W2039337032 @default.
• W2750536031 cites W2043659905 @default.
• W2750536031 cites W2044433401 @default.
• W2750536031 cites W2044992381 @default.
• W2750536031 cites W2050864169 @default.
• W2750536031 cites W2054032180 @default.
• W2750536031 cites W2054042288 @default.
• W2750536031 cites W2055732173 @default.
• W2750536031 cites W2059128083 @default.
• W2750536031 cites W2065054017 @default.
• W2750536031 cites W2068234766 @default.
• W2750536031 cites W2069850690 @default.
• W2750536031 cites W2074258019 @default.
• W2750536031 cites W2074768718 @default.
• W2750536031 cites W2077553363 @default.
• W2750536031 cites W2080202443 @default.
• W2750536031 cites W2083085047 @default.
• W2750536031 cites W2083089709 @default.
• W2750536031 cites W2083102356 @default.
• W2750536031 cites W2084567246 @default.
• W2750536031 cites W2090348764 @default.
• W2750536031 cites W2099146158 @default.
• W2750536031 cites W2102144390 @default.
• W2750536031 cites W2112133235 @default.
• W2750536031 cites W2112866067 @default.
• W2750536031 cites W2113906692 @default.
• W2750536031 cites W2118403212 @default.
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• W2750536031 cites W2142477379 @default.
• W2750536031 cites W2143523733 @default.
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• W2750536031 cites W2146688138 @default.
• W2750536031 cites W2146908354 @default.
• W2750536031 cites W2150968312 @default.
• W2750536031 cites W2158303916 @default.
• W2750536031 cites W2160834915 @default.
• W2750536031 cites W2161868263 @default.
• W2750536031 cites W2168470080 @default.
• W2750536031 cites W2171190137 @default.
• W2750536031 cites W2172283401 @default.
• W2750536031 cites W2185075416 @default.
• W2750536031 cites W2262414037 @default.
• W2750536031 cites W2278665679 @default.
• W2750536031 cites W2317340981 @default.
• W2750536031 cites W2338446464 @default.
• W2750536031 cites W2415094114 @default.
• W2750536031 cites W2468717730 @default.
• W2750536031 cites W2479232428 @default.
• W2750536031 cites W2520338075 @default.
• W2750536031 cites W2531319683 @default.
• W2750536031 cites W2534292219 @default.
• W2750536031 cites W2544465393 @default.
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• W2750536031 doi "https://doi.org/10.1136/esmoopen-2017-000218" @default.
• W2750536031 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5703395" @default.
• W2750536031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29209524" @default.
• W2750536031 hasPublicationYear "2017" @default.
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