SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2750673208> ?p ?o ?g. }

Showing items 1 to 100 of ±131 with 100 items per page.

W2750673208 endingPage "709" @default.
W2750673208 startingPage "700" @default.
W2750673208 abstract "The post-transcriptional regulator CsrA regulates multiple unrelated processes such as central carbon metabolism, motility, biofilm formation and bacterial virulence in different bacteria. However, regulation by CsrA in enterohemorrhagic Escherichia coli (EHEC) O157:H7 is still largely unknown. In this study, we performed a detailed analysis of gene expression differences between the EHEC O157:H7 wild-type strain and a corresponding csrA::kan mutant using RNA-seq technology. Genes whose expression was affected by CsrA were identified and grouped into different clusters of orthologous group categories. Genes located in the locus of enterocyte effacement (LEE) pathogenicity island were significantly upregulated, whereas expression of flagella-related genes was significantly reduced in the csrA::kan mutant. Subsequent bacterial adherence and motility assays showed that inactivation of CsrA in EHEC O157:H7 resulted in a significant increase in bacterial adherence to host epithelial cells, with a concomitant loss of swimming motility on semi-solid agar plates. Furthermore, we also found that CsrA regulates genes not previously identified in other bacterial species, including genes encoding cytochrome oxidases and those required for nitrogen metabolism. Our results provide essential insight into the regulatory function of CsrA." @default.
W2750673208 created "2017-09-15" @default.
W2750673208 creator A5043545770 @default.
W2750673208 creator A5056925804 @default.
W2750673208 creator A5073754378 @default.
W2750673208 date "2017-10-01" @default.
W2750673208 modified "2023-09-23" @default.
W2750673208 title "Global effect of CsrA on gene expression in enterohemorrhagic Escherichia coli O157:H7" @default.
W2750673208 cites W1531784797 @default.
W2750673208 cites W1545800501 @default.
W2750673208 cites W1573786785 @default.
W2750673208 cites W1579607832 @default.
W2750673208 cites W1595340441 @default.
W2750673208 cites W1874993960 @default.
W2750673208 cites W1878448296 @default.
W2750673208 cites W1885356084 @default.
W2750673208 cites W1886047588 @default.
W2750673208 cites W1887891256 @default.
W2750673208 cites W1895859646 @default.
W2750673208 cites W1909924417 @default.
W2750673208 cites W1945783569 @default.
W2750673208 cites W1967605214 @default.
W2750673208 cites W1975057095 @default.
W2750673208 cites W2005671217 @default.
W2750673208 cites W2010145789 @default.
W2750673208 cites W2028440663 @default.
W2750673208 cites W2035922299 @default.
W2750673208 cites W2039591953 @default.
W2750673208 cites W2042065648 @default.
W2750673208 cites W2045765967 @default.
W2750673208 cites W2046173213 @default.
W2750673208 cites W2051347791 @default.
W2750673208 cites W2064855802 @default.
W2750673208 cites W2079308952 @default.
W2750673208 cites W2081304299 @default.
W2750673208 cites W2082291851 @default.
W2750673208 cites W2086248824 @default.
W2750673208 cites W2096691897 @default.
W2750673208 cites W2099210628 @default.
W2750673208 cites W2101058428 @default.
W2750673208 cites W2107277218 @default.
W2750673208 cites W2108705527 @default.
W2750673208 cites W2111798689 @default.
W2750673208 cites W2112111992 @default.
W2750673208 cites W2113094778 @default.
W2750673208 cites W2114104545 @default.
W2750673208 cites W2116137883 @default.
W2750673208 cites W2121890546 @default.
W2750673208 cites W2131198658 @default.
W2750673208 cites W2134039538 @default.
W2750673208 cites W2140944735 @default.
W2750673208 cites W2143502465 @default.
W2750673208 cites W2144963709 @default.
W2750673208 cites W2146840544 @default.
W2750673208 cites W2147761472 @default.
W2750673208 cites W2150105112 @default.
W2750673208 cites W2157692689 @default.
W2750673208 cites W2162773926 @default.
W2750673208 cites W2164989938 @default.
W2750673208 cites W2171983532 @default.
W2750673208 cites W2419445131 @default.
W2750673208 cites W2599380304 @default.
W2750673208 cites W4245245389 @default.
W2750673208 cites W4255137461 @default.
W2750673208 cites W4295850018 @default.
W2750673208 doi "https://doi.org/10.1016/j.resmic.2017.08.003" @default.
W2750673208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28870757" @default.
W2750673208 hasPublicationYear "2017" @default.
W2750673208 type Work @default.
W2750673208 sameAs 2750673208 @default.
W2750673208 citedByCount "18" @default.
W2750673208 countsByYear W27506732082018 @default.
W2750673208 countsByYear W27506732082019 @default.
W2750673208 countsByYear W27506732082020 @default.
W2750673208 countsByYear W27506732082021 @default.
W2750673208 countsByYear W27506732082022 @default.
W2750673208 countsByYear W27506732082023 @default.
W2750673208 crossrefType "journal-article" @default.
W2750673208 hasAuthorship W2750673208A5043545770 @default.
W2750673208 hasAuthorship W2750673208A5056925804 @default.
W2750673208 hasAuthorship W2750673208A5073754378 @default.
W2750673208 hasConcept C104317684 @default.
W2750673208 hasConcept C115811362 @default.
W2750673208 hasConcept C143065580 @default.
W2750673208 hasConcept C150194340 @default.
W2750673208 hasConcept C165864922 @default.
W2750673208 hasConcept C180223184 @default.
W2750673208 hasConcept C54355233 @default.
W2750673208 hasConcept C547475151 @default.
W2750673208 hasConcept C58207958 @default.
W2750673208 hasConcept C60987743 @default.
W2750673208 hasConcept C62130838 @default.
W2750673208 hasConcept C86803240 @default.
W2750673208 hasConcept C89423630 @default.
W2750673208 hasConceptScore W2750673208C104317684 @default.
W2750673208 hasConceptScore W2750673208C115811362 @default.
W2750673208 hasConceptScore W2750673208C143065580 @default.
W2750673208 hasConceptScore W2750673208C150194340 @default.