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- W2750872990 abstract "This section looks forward to the future of neural tissue engineering. It examines several new and exciting technologies for manipulating cell behavior. This chapter covers the development of organoids, 3D bioprinting, direct conversion of adult cells into functional neural cells, gene editing, and controlling neural cell behavior using cues, including light and designer molecules. Traditional tissue engineering approaches can be adopted to work in combination with some of these new technologies discussed in this chapter. The inherent properties of pluripotent stem cells can be harnessed to engineer organoids—mini tissues that possess the structures and properties of the tissues found in the nervous system. 3D bioprinting uses bioinks derived from both natural and synthetic materials in combination with stem cells to fabricate 3D functional tissues. Another increasingly popular tissue engineering approach works by directly reprogramming other mature cell types into functional neural tissues. This strategy can be implemented both in vitro and in vivo and both of these processes will be discussed in this chapter. Directly reprogramming adult cells into neural tissue serves as an interesting approach to tissue engineering as it avoids the use of stem cells, which has certain advantages for clinical translation. Next, the process of gene editing alters the cellular genome, providing a novel way of controlling the behavior and phenotypes of cells being modified. Finally, the use of optogenetics and Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) provide ways of controlling neural cell behavior, using light and chemicals, respectively. All of these recently developed tools enhance our ability to engineer neural tissue from cells and they provide greater insight into how the nervous system functions." @default.
- W2750872990 created "2017-09-15" @default.
- W2750872990 creator A5089438441 @default.
- W2750872990 date "2017-01-01" @default.
- W2750872990 modified "2023-10-18" @default.
- W2750872990 title "New technologies for engineering neural tissue from stem cells" @default.
- W2750872990 cites W1771186062 @default.
- W2750872990 cites W1828637994 @default.
- W2750872990 cites W1862832045 @default.
- W2750872990 cites W1874729010 @default.
- W2750872990 cites W1886661780 @default.
- W2750872990 cites W1932303130 @default.
- W2750872990 cites W1950098865 @default.
- W2750872990 cites W1966403223 @default.
- W2750872990 cites W1967299354 @default.
- W2750872990 cites W1968310639 @default.
- W2750872990 cites W1982397697 @default.
- W2750872990 cites W1985958520 @default.
- W2750872990 cites W1987167495 @default.
- W2750872990 cites W1987171954 @default.
- W2750872990 cites W1991073029 @default.
- W2750872990 cites W1999311112 @default.
- W2750872990 cites W1999834009 @default.
- W2750872990 cites W2001419937 @default.
- W2750872990 cites W2003171404 @default.
- W2750872990 cites W2008649912 @default.
- W2750872990 cites W2013709818 @default.
- W2750872990 cites W2016648814 @default.
- W2750872990 cites W2018286352 @default.
- W2750872990 cites W2026920679 @default.
- W2750872990 cites W2028306551 @default.
- W2750872990 cites W2030495029 @default.
- W2750872990 cites W2031195065 @default.
- W2750872990 cites W2044347158 @default.
- W2750872990 cites W2045435533 @default.
- W2750872990 cites W2047918294 @default.
- W2750872990 cites W2049717499 @default.
- W2750872990 cites W2053911973 @default.
- W2750872990 cites W2056177992 @default.
- W2750872990 cites W2061184966 @default.
- W2750872990 cites W2064815984 @default.
- W2750872990 cites W2064886170 @default.
- W2750872990 cites W2068478010 @default.
- W2750872990 cites W2073063983 @default.
- W2750872990 cites W2074131381 @default.
- W2750872990 cites W2074314696 @default.
- W2750872990 cites W2078308455 @default.
- W2750872990 cites W2089771991 @default.
- W2750872990 cites W2090179846 @default.
- W2750872990 cites W2090350083 @default.
- W2750872990 cites W2095546080 @default.
- W2750872990 cites W2112444085 @default.
- W2750872990 cites W2125524975 @default.
- W2750872990 cites W2125987139 @default.
- W2750872990 cites W2136541538 @default.
- W2750872990 cites W2138977668 @default.
- W2750872990 cites W2140494588 @default.
- W2750872990 cites W2143296478 @default.
- W2750872990 cites W2146646098 @default.
- W2750872990 cites W2156257459 @default.
- W2750872990 cites W2160092129 @default.
- W2750872990 cites W2161370512 @default.
- W2750872990 cites W2167095271 @default.
- W2750872990 cites W2195294260 @default.
- W2750872990 cites W2203238184 @default.
- W2750872990 cites W2205546371 @default.
- W2750872990 cites W2212633910 @default.
- W2750872990 cites W2235428790 @default.
- W2750872990 cites W2265498315 @default.
- W2750872990 cites W2275148408 @default.
- W2750872990 cites W2299693612 @default.
- W2750872990 cites W2311770845 @default.
- W2750872990 cites W2317565849 @default.
- W2750872990 cites W2331824792 @default.
- W2750872990 cites W2341041396 @default.
- W2750872990 cites W2344675989 @default.
- W2750872990 cites W2346484133 @default.
- W2750872990 cites W2356757232 @default.
- W2750872990 cites W2394524191 @default.
- W2750872990 cites W2398741820 @default.
- W2750872990 cites W2414665289 @default.
- W2750872990 cites W2416402039 @default.
- W2750872990 cites W2465910223 @default.
- W2750872990 cites W2499249264 @default.
- W2750872990 cites W2508292514 @default.
- W2750872990 cites W2510157877 @default.
- W2750872990 cites W2524820142 @default.
- W2750872990 cites W2537137139 @default.
- W2750872990 cites W2540916512 @default.
- W2750872990 cites W2551225568 @default.
- W2750872990 cites W2560195193 @default.
- W2750872990 cites W2560474498 @default.
- W2750872990 cites W2561729692 @default.
- W2750872990 cites W2582066004 @default.
- W2750872990 doi "https://doi.org/10.1016/b978-0-12-811385-1.00008-x" @default.
- W2750872990 hasPublicationYear "2017" @default.
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