Matches in SemOpenAlex for { <https://semopenalex.org/work/W2750978436> ?p ?o ?g. }
- W2750978436 endingPage "120" @default.
- W2750978436 startingPage "112" @default.
- W2750978436 abstract "Abstract Reversible methylation by means of N6-methyladenosine (m6A) is the most prevalent internal modification in mammalian mRNA. This RNA chemical mark is created by proteins that are m6A “writers” and can be reversed by proteins that are m6A “erasers” (i.e., demethylases). Some other proteins serving as “readers” can recognize m6A-containing mRNA and regulate downstream molecular mechanisms accordingly. Although m6A bases in RNA perform critical functions in important biological processes, their roles in cancer biology and cancer stem cells remain largely unknown. In this review, we focus on the m6A-associated mechanisms and modification landscapes in several major malignant tumors. Global and detailed analyses were both conducted on relevant high-throughput sequencing data. Possible interventions against m6A demethylases are also explored in this review, which may be advantageous for the treatment of m6A related cancers." @default.
- W2750978436 created "2017-09-15" @default.
- W2750978436 creator A5001839093 @default.
- W2750978436 creator A5014068004 @default.
- W2750978436 creator A5035012975 @default.
- W2750978436 creator A5041116056 @default.
- W2750978436 creator A5046380471 @default.
- W2750978436 creator A5046849313 @default.
- W2750978436 creator A5053755264 @default.
- W2750978436 creator A5056384869 @default.
- W2750978436 creator A5058207776 @default.
- W2750978436 creator A5069913517 @default.
- W2750978436 creator A5074516731 @default.
- W2750978436 creator A5088684298 @default.
- W2750978436 date "2017-11-01" @default.
- W2750978436 modified "2023-10-14" @default.
- W2750978436 title "Roles of RNA methylation by means of N6-methyladenosine (m6A) in human cancers" @default.
- W2750978436 cites W1527564187 @default.
- W2750978436 cites W1555039175 @default.
- W2750978436 cites W1559438287 @default.
- W2750978436 cites W1895681508 @default.
- W2750978436 cites W1924636346 @default.
- W2750978436 cites W1941339056 @default.
- W2750978436 cites W1968051054 @default.
- W2750978436 cites W1978013460 @default.
- W2750978436 cites W1980556041 @default.
- W2750978436 cites W1981629946 @default.
- W2750978436 cites W1986955775 @default.
- W2750978436 cites W1987243580 @default.
- W2750978436 cites W1989683090 @default.
- W2750978436 cites W1990439966 @default.
- W2750978436 cites W1991058622 @default.
- W2750978436 cites W1991807334 @default.
- W2750978436 cites W1997453048 @default.
- W2750978436 cites W2002698073 @default.
- W2750978436 cites W2007429249 @default.
- W2750978436 cites W2009315890 @default.
- W2750978436 cites W2009995861 @default.
- W2750978436 cites W2011400542 @default.
- W2750978436 cites W2022770379 @default.
- W2750978436 cites W2024117723 @default.
- W2750978436 cites W2028335133 @default.
- W2750978436 cites W2032514134 @default.
- W2750978436 cites W2045281368 @default.
- W2750978436 cites W2045584911 @default.
- W2750978436 cites W2060676431 @default.
- W2750978436 cites W2064614845 @default.
- W2750978436 cites W2065847836 @default.
- W2750978436 cites W2070349398 @default.
- W2750978436 cites W2071930821 @default.
- W2750978436 cites W2075160563 @default.
- W2750978436 cites W2077936726 @default.
- W2750978436 cites W2080004564 @default.
- W2750978436 cites W2083734066 @default.
- W2750978436 cites W2084304177 @default.
- W2750978436 cites W2084588717 @default.
- W2750978436 cites W2085106808 @default.
- W2750978436 cites W2085278634 @default.
- W2750978436 cites W2088817968 @default.
- W2750978436 cites W2089390825 @default.
- W2750978436 cites W2089622611 @default.
- W2750978436 cites W2091235283 @default.
- W2750978436 cites W2091724447 @default.
- W2750978436 cites W2093764457 @default.
- W2750978436 cites W2093901546 @default.
- W2750978436 cites W2094247278 @default.
- W2750978436 cites W2097660065 @default.
- W2750978436 cites W2102118972 @default.
- W2750978436 cites W2102872651 @default.
- W2750978436 cites W2106787323 @default.
- W2750978436 cites W2110678911 @default.
- W2750978436 cites W2111163869 @default.
- W2750978436 cites W2113593386 @default.
- W2750978436 cites W2114970231 @default.
- W2750978436 cites W2117889142 @default.
- W2750978436 cites W2122767064 @default.
- W2750978436 cites W2122969281 @default.
- W2750978436 cites W2123032740 @default.
- W2750978436 cites W2137052325 @default.
- W2750978436 cites W2137318078 @default.
- W2750978436 cites W2140277442 @default.
- W2750978436 cites W2141458291 @default.
- W2750978436 cites W2152333235 @default.
- W2750978436 cites W2152820917 @default.
- W2750978436 cites W2158228067 @default.
- W2750978436 cites W2164852392 @default.
- W2750978436 cites W2165547003 @default.
- W2750978436 cites W2166608208 @default.
- W2750978436 cites W2167149089 @default.
- W2750978436 cites W2169494000 @default.
- W2750978436 cites W2170552969 @default.
- W2750978436 cites W2170830174 @default.
- W2750978436 cites W2172359919 @default.
- W2750978436 cites W2180404227 @default.
- W2750978436 cites W2201760124 @default.
- W2750978436 cites W2255613730 @default.
- W2750978436 cites W2269054226 @default.
- W2750978436 cites W2272984102 @default.